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Promising two-photon probes for in vivo detection of beta amyloid deposits
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology.ORCID iD: 0000-0003-0185-5724
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology. Wroclaw Univ Technol, Poland.
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2014 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 50, no 79, p. 11694-11697Article in journal (Refereed) Published
Abstract [en]

Based on electronic structure calculations we propose that particular small-sized organic molecules - donor-acceptor substituted phenyl polymethines - can be used as two-photon diagnostic probes for non-invasive imaging of amyloid oligomers and fibrils, which are often referred to as the "early signatures'' of Alzheimer's disease.

Place, publisher, year, edition, pages
2014. Vol. 50, no 79, p. 11694-11697
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Chemical Sciences
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URN: urn:nbn:se:kth:diva-154776DOI: 10.1039/c4cc03897eISI: 000342069600017OAI: oai:DiVA.org:kth-154776DiVA, id: diva2:759649
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QC 20141030

Available from: 2014-10-30 Created: 2014-10-27 Last updated: 2017-12-05Bibliographically approved

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Murugan, N. ArulÅgren, Hans

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