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Promising two-photon probes for in vivo detection of beta amyloid deposits
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology.ORCID iD: 0000-0003-0185-5724
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology. Wroclaw Univ Technol, Poland.
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2014 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 50, no 79, 11694-11697 p.Article in journal (Refereed) Published
Abstract [en]

Based on electronic structure calculations we propose that particular small-sized organic molecules - donor-acceptor substituted phenyl polymethines - can be used as two-photon diagnostic probes for non-invasive imaging of amyloid oligomers and fibrils, which are often referred to as the "early signatures'' of Alzheimer's disease.

Place, publisher, year, edition, pages
2014. Vol. 50, no 79, 11694-11697 p.
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Chemical Sciences
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URN: urn:nbn:se:kth:diva-154776DOI: 10.1039/c4cc03897eISI: 000342069600017OAI: oai:DiVA.org:kth-154776DiVA: diva2:759649
Note

QC 20141030

Available from: 2014-10-30 Created: 2014-10-27 Last updated: 2017-12-05Bibliographically approved

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Murugan, N. ArulÅgren, Hans

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