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A Novel Picornavirus Associated with Gastroenteritis
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2009 (English)In: Journal of Virology, ISSN 0022-538X, E-ISSN 1098-5514, Vol. 83, no 22, 12002-12006 p.Article in journal (Refereed) Published
Abstract [en]

A novel picornavirus genome was sequenced, showing 42.6%, 35.2%, and 44.6% of deduced amino acid identities corresponding to the P1, P2, and P3 regions, respectively, of the Aichi virus. Divergent strains of this new virus, which we named salivirus, were detected in 18 stool samples from Nigeria, Tunisia, Nepal, and the United States. A statistical association was seen between virus shedding and unexplained cases of gastroenteritis in Nepal (P = 0.0056). Viruses with approximately 90% nucleotide similarity, named klassevirus, were also recently reported in three cases of unexplained diarrhea from the United States and Australia and in sewage from Spain, reflecting a global distribution and supporting a pathogenic role for this new group of picornaviruses.

Place, publisher, year, edition, pages
2009. Vol. 83, no 22, 12002-12006 p.
National Category
Microbiology in the medical area
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URN: urn:nbn:se:kth:diva-159901DOI: 10.1128/JVI.01241-09ISI: 000271084100059PubMedID: 19759142Scopus ID: 2-s2.0-70350314339OAI: oai:DiVA.org:kth-159901DiVA: diva2:787647
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QC 20150211

Available from: 2015-02-11 Created: 2015-02-11 Last updated: 2017-12-04Bibliographically approved

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