Change search
ReferencesLink to record
Permanent link

Direct link
Sustained prognostic implications of newly detected glucose abnormalities in patients with acute myocardial infarction: Longterm follow-up of the Glucose Tolerance in Patients with Acute Myocardial Infarction cohort
KTH, School of Architecture and the Built Environment (ABE), Transport Science, Transport planning, economics and engineering.ORCID iD: 0000-0001-7606-8771
Show others and affiliations
2015 (English)In: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 12, no 1, 23-32 p.Article in journal (Refereed) Published
Abstract [en]

Objective: To investigate long-term prognostic importance of newly discovered glucose disturbances in patients with acute myocardial infarction (AMI). Methods: During 1998-2001, consecutive patients with AMI (n=167) and healthy controls (n=184) with no previously known diabetes were investigated with an oral glucose tolerance test (OGTT). Patients and controls were separately followed up for cardiovascular events (first of cardiovascular mortality/AMI/stroke/heart failure) during a decade. Results: In all, 68% of the patients and 35% of the controls had newly detected abnormal glucose tolerance (AGT). Cardiovascular event (n=72, p=0.0019) and cardiovascular mortality (n=31, p=0.031) were more frequent in patients with newly detected AGT. Regarding patients, a Cox proportional-hazard regression analysis identified AGT (hazard ratio (HR): 2.30; 95% confidence interval (CI): 1.24-4.25; p=0.008) and previous AMI (HR: 2.39; CI: 1.31-4.35; p=0.004) as prognostically important. Conclusion: An OGTT at discharge after AMI disclosed a high proportion of patients with previously unknown AGT which had a significant and independent association with long-term prognosis.

Place, publisher, year, edition, pages
2015. Vol. 12, no 1, 23-32 p.
Keyword [en]
Myocardial infarction, prognosis, diabetes, impaired glucose tolerance, oral glucose tolerance test
National Category
Endocrinology and Diabetes
URN: urn:nbn:se:kth:diva-160053DOI: 10.1177/1479164114551746ISI: 000346345200003ScopusID: 2-s2.0-84916908631OAI: diva2:793136
Swedish Heart Lung Foundation

QC 20150306

Available from: 2015-03-06 Created: 2015-02-13 Last updated: 2015-03-06Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Näsman, Per
By organisation
Transport planning, economics and engineering
In the same journal
Diabetes & Vascular Disease Research
Endocrinology and Diabetes

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 11 hits
ReferencesLink to record
Permanent link

Direct link