Modelling the heart with the atrioventricular plane as a piston unit
2015 (English)In: Medical Engineering and Physics, ISSN 1350-4533, E-ISSN 1873-4030, Vol. 37, no 1, 87-92 p.Article in journal (Refereed) Published
Medical imaging and clinical studies have proven that the heart pumps by means of minor outer volume changes and back-and-forth longitudinal movements in the atrioventricular (AV) region. The magnitude of AV-plane displacement has also shown to be a reliable index for diagnosis of heart failure. Despite this, AV-plane displacement is usually omitted from cardiovascular modelling. We present a lumped-parameter cardiac model in which the heart is described as a displacement pump with the AV plane functioning as a piston unit (AV piston). This unit is constructed of different upper and lower areas analogous with the difference in the atrial and ventricular cross-sections. The model output reproduces normal physiology, with a left ventricular pressure in the range of 8-130 mmHg, an atrial pressure of approximatly 9 mmHg, and an arterial pressure change between 75 mmHg and 130 mmHg. In addition, the model reproduces the direction of the main systolic and diastolic movements of the AV piston with realistic velocity magnitude (similar to 10 cm/s). Moreover, changes in the simulated systolic ventricular-contraction force influence diastolic filling, emphasizing the coupling between cardiac systolic and diastolic functions. The agreement between the simulation and normal physiology highlights the importance of myocardial longitudinal movements and of atrioventricular interactions in cardiac pumping.
Place, publisher, year, edition, pages
2015. Vol. 37, no 1, 87-92 p.
Atrioventricular interaction, Cardiac function, Cardiac pumping, Longitudinal function, Cardiac model, Bond graphs
Biomedical Laboratory Science/Technology
IdentifiersURN: urn:nbn:se:kth:diva-161634DOI: 10.1016/j.medengphy.2014.11.002ISI: 000349585100011PubMedID: 25466260ScopusID: 2-s2.0-84920913473OAI: oai:DiVA.org:kth-161634DiVA: diva2:797615
QC 201503242015-03-242015-03-132015-03-24Bibliographically approved