Ultrasensitive and label-free molecular-level detection enabled by light phase control in magnetoplasmonic nanoantennas
2015 (English)In: Nature Communications, ISSN 2041-1723, Vol. 6, 6150Article in journal (Refereed) Published
Systems allowing label-free molecular detection are expected to have enormous impact on biochemical sciences. Research focuses on materials and technologies based on exploiting localized surface plasmon resonances in metallic nanostructures. The reason for this focused attention is their suitability for single-molecule sensing, arising from intrinsically nanoscopic sensing volume and the high sensitivity to the local environment. Here we propose an alternative route, which enables radically improved sensitivity compared with recently reported plasmon-based sensors. Such high sensitivity is achieved by exploiting the control of the phase of light in magnetoplasmonic nanoantennas. We demonstrate a manifold improvement of refractometric sensing figure-of-merit. Most remarkably, we show a raw surface sensitivity (that is, without applying fitting procedures) of two orders of magnitude higher than the current values reported for nanoplasmonic sensors. Such sensitivity corresponds to a mass of similar to 0.8 ag per nanoantenna of polyamide-6.6 (n = 1.51), which is representative for a large variety of polymers, peptides and proteins.
Place, publisher, year, edition, pages
2015. Vol. 6, 6150
IdentifiersURN: urn:nbn:se:kth:diva-161972DOI: 10.1038/ncomms7150ISI: 000350203400001PubMedID: 25639190ScopusID: 2-s2.0-84923113810OAI: oai:DiVA.org:kth-161972DiVA: diva2:800569
FunderEU, European Research Council, 257654Swedish Research CouncilSwedish Foundation for Strategic Research , RMA08
QC 201504072015-04-072015-03-202015-04-07Bibliographically approved