Functional porous membranes from amorphous linear dendritic polyester hybrids
2015 (English)In: Polymer Chemistry, ISSN 1759-9954, Vol. 6, no 13, 2390-2395 p.Article in journal (Refereed) Published
By combining ATRP, dendrimer chemistry and 'click' reactions, a library of novel linear dendritic block copolymers (hybrids) was successfully synthesized. The isolated polymers displayed hydrophilic alkyne groups and T-g's ranging from 14 degrees C to 67 degrees C. A T-g threshold of 39 degrees C was found necessary for straightforward porous membrane fabrication via the breath figure method. Exploiting the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, a robust and benign protocol was identified enabling surface functionalization under aqueous conditions. Such manipulations included the introduction of fluorescent rhodamine for thorough assessment by confocal fluorescence microscopy as well as polyethylene glycol chains or perfluorinated groups for tuning the membrane wettability. Finally, with the initial indication of being nontoxic to human dermal fibroblasts (hDF) and osteoblast-like MG63, the porous membranes can potentially find use in the field of controlled cell culture such as patterning of cell growth.
Place, publisher, year, edition, pages
2015. Vol. 6, no 13, 2390-2395 p.
IdentifiersURN: urn:nbn:se:kth:diva-164488DOI: 10.1039/c4py01803fISI: 000351493500004ScopusID: 2-s2.0-84925004535OAI: oai:DiVA.org:kth-164488DiVA: diva2:806320
QC 201504202015-04-202015-04-172015-05-20Bibliographically approved