Centrifugal microfluidic system for rapid, low-cost HIV diagnosis: CD4+ T-cell counting using an integrated DVD platform
2012 (English)In: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, Chemical and Biological Microsystems Society , 2012, 1942-1944 p.Conference paper (Refereed)
HIV is a pandemic that currently threatens over 33 million lives worldwide and HIV/AIDS remains one of the major causes of death globally. The continued monitoring of the CD4+ T-lymphocytes count in HIV patients is necessary for proper treatment, although this testing is too expensive and complex for limited resource settings. We report on a novel integrated centrifugal (CD) microfluidic system for rapid and low-cost HIV diagnosis through automated counting of CD4+ T-cells for point-of-care applications. We demonstrate the integrated T-cell immunocapture and detection mechanism using a novel system comprised of a modified commercial DVD drive and polymer disc.
Place, publisher, year, edition, pages
Chemical and Biological Microsystems Society , 2012. 1942-1944 p.
Centrifugal microfluidics, HIV diagnostics, Immunocapture
IdentifiersURN: urn:nbn:se:kth:diva-165131ScopusID: 2-s2.0-84901758262ISBN: 9780979806452OAI: oai:DiVA.org:kth-165131DiVA: diva2:807495
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, 28 October 2012 through 1 November 2012, Okinawa, Japan
QC 201504232015-04-232015-04-232015-04-23Bibliographically approved