Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides
2015 (English)In: Carbohydrate Research, ISSN 0008-6215, E-ISSN 1873-426X, Vol. 405, 33-38 p.Article in journal (Refereed) Published
Carbohydrate-functionalized single-walled carbon nanotubes (SWNTs) were synthesized using microwave-assisted reaction of perfluorophenyl azide with the nanotubes. The results showed that microwave radiation provides a rapid and effective means to covalently attach carbohydrates to SWNTs, producing carbohydrate-SWNT conjugates for biorecognition. The carbohydrate-functionalized SWNTs were furthermore shown to interact specifically with cognate carbohydrate-specific proteins (lectins), resulting in predicted recognition patterns. The carbohydrate-presenting SWNTs constitute a new platform for sensitive protein-or cell recognition, which pave the way for glycoconjugated carbon nanomaterials in biorecognition applications.
Place, publisher, year, edition, pages
2015. Vol. 405, 33-38 p.
Single-walled carbon nanotubes, Microwave, Perfluorophenyl azide, Covalent functionalization, Carbohydrate, Lectin
IdentifiersURN: urn:nbn:se:kth:diva-163964DOI: 10.1016/j.carres.2014.09.006ISI: 000350748400005PubMedID: 25746392ScopusID: 2-s2.0-84924200153OAI: oai:DiVA.org:kth-163964DiVA: diva2:809792
Correction in: Carbohydrate Research, Vol. 412, article number 6968, DOI: 10.1016/j.carres.2015.03.013, WOS: 000357542000012, Scopus: 2-s2.0-849347531872015-05-052015-04-132015-09-07Bibliographically approved