Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD): A functional near-infrared spectroscopy study
2015 (English)In: Biomedical Optics Express, ISSN 2156-7085, Vol. 6, no 3, 690-701 p.Article in journal (Refereed) Published
Autism spectrum disorder (ASD) is a neuro-developmental disorder, characterized by impairments in one's capacity for joint attention. In this study, functional near-infrared spectroscopy (fNIRS) was applied to study the differences in activation and functional connectivity in the prefrontal cortex between children with autism spectrum disorder (ASD) and typically developing (TD) children. 21 ASD and 20 TD children were recruited to perform joint and non-joint attention tasks. Compared with TD children, children with ASD showed reduced activation and atypical functional connectivity pattern in the prefrontal cortex during joint attention. The atypical development of left prefrontal cortex might play an important role in social cognition defects of children with ASD.
Place, publisher, year, edition, pages
2015. Vol. 6, no 3, 690-701 p.
IdentifiersURN: urn:nbn:se:kth:diva-164006DOI: 10.1364/BOE.6.000690ISI: 000350802000004PubMedID: 25798296ScopusID: 2-s2.0-84942367401OAI: oai:DiVA.org:kth-164006DiVA: diva2:809850
QC 201505052015-05-052015-04-132015-05-05Bibliographically approved