Degradation product profiles of melt spun in situ cross-linked poly(epsilon-caprolactone) fibers
2015 (English)In: Materials Chemistry and Physics, ISSN 0254-0584, Vol. 156, 82-88 p.Article in journal (Refereed) Published
In situ cross-linking of poly(epsilon-caprolactone) (PCL) fiber with bis-(epsilon-caprolactone-4-yl) (BCY) was shown to be a feasible approach to compensate for reduction in molar mass of PCL during melt-spinning. The effect of in situ cross-linking on the degradation profile of melt spun PCL fibers with different amounts of BCY was evaluated using electrospray ionization-mass spectrometry. Degradation of the cross-linked fibers was carried out in aqueous medium at 37 degrees C and 60 degrees C for different periods of time. The degradation profiles were then compared with uncross-linked fiber and 3D porous cross-linked film of PCL Interesting differences in the degradation product profiles with linear, cyclic or BCY-related low molar mass compounds were observed, clearly demonstrating the effect of cross-linking and processing on the degradation process and formation of water-soluble products. In addition the degradation product profiles demonstrated that in situ cross-linking is a feasible technique for counteracting degradation reactions during melt-spinning.
Place, publisher, year, edition, pages
2015. Vol. 156, 82-88 p.
Biomaterials, Polymers, Aging, Electron microscopy
IdentifiersURN: urn:nbn:se:kth:diva-166321DOI: 10.1016/j.matchemphys.2015.02.028ISI: 000352667300011ScopusID: 2-s2.0-84925233518OAI: oai:DiVA.org:kth-166321DiVA: diva2:811215
QC 201505112015-05-112015-05-072015-05-11Bibliographically approved