Numerical simulation of a deformable cell in microchannels
2013 (English)In: Computational Methods for Coupled Problems in Science and Engineering V: A Conference Celebrating the 60th Birthday of Eugenio Onate, COUPLED PROBLEMS 2013, 2013, 685-695 p.Conference paper (Refereed)
The main goal of this work is to numerically investigate the behavior of a cell flowing in a microfluidic system. In particular, we want to model flow-induced deformations of an isolated cell to quantitatively evaluate the cell response when subjected to a representative range of flow rates in a realistic geometry, with specific interest in the case of cell trapping. This research will help optimize operating conditions as well as the design of cell manipulation/culture micro-devices, so as to guarantee cell viability and ultimately improve high-throughput performance.
Place, publisher, year, edition, pages
2013. 685-695 p.
Computing methods, Coupled problems, FSI, Single-cell
IdentifiersURN: urn:nbn:se:kth:diva-168778ISI: 000345147900060ScopusID: 2-s2.0-84906875284ISBN: 978-849414076-1OAI: oai:DiVA.org:kth-168778DiVA: diva2:820432
5th International Conference on Computational Methods for Coupled Problems in Science and Engineering, COUPLED PROBLEMS 2013; Santa Eulalia, Ibiza Island; Spain
QC 201506122015-06-122015-06-092015-06-12Bibliographically approved