Estimation of arterial stiffness through pulse transit time measurement
2014 (English)In: BIODEVICES 2014 - 7th Int. Conference on Biomedical Electronics and Devices, Proceedings; Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014, 2014, 238-242 p.Conference paper (Refereed)
Early detection of cardiovascular disease (CVD) and its treatment is significantly expected to reduce the mortality rate across the world. While several diagnostic techniques have been developed for early detection of the CVD, recent focus has been on measuring the 'arterial stiffness', which appears to be a major indicator of onset of cardio vascular disease. In this work, authors consider three mathematical models that relate pulse wave velocity (PWV) with arterial stiffness. While one model considers blood to be a nonviscous and incompressible fluid, the other considers it to be a viscous and compressible. Pulse transit time has been measured experimentally for five different individuals of different ages and heights from where PWV has been estimated. Using values of PWV, Young's modulus of elasticity has been derived. Data related to arteries such as radius, wall thickness, density and viscosity of blood have been taken from published literature where these parameters have been measured using techniques such as MRI. Initial results indicate that different models predict different estimates for arterial stiffness that depend on assumptions made.
Place, publisher, year, edition, pages
2014. 238-242 p.
Arterial striffness, Cardio-vascular disease, Pulse transit time, Pulse wave velocity, Acoustic wave velocity, Biomedical engineering, Blood, Diagnosis, Elastic moduli, Electronic medical equipment, Incompressible flow, Mathematical models, Arterial stiffness, Diagnostic techniques, Incompressible fluid, Wall thickness, Stiffness
Health Care Service and Management, Health Policy and Services and Health Economy
IdentifiersURN: urn:nbn:se:kth:diva-167891ScopusID: 2-s2.0-84902323932ISBN: 9789897580130OAI: oai:DiVA.org:kth-167891DiVA: diva2:821194
7th International Conference on Biomedical Electronics and Devices, BIODEVICES 2014 - Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014, 3 March 2014 through 6 March 2014, Angers, Loire Valley
QC 201506152015-06-152015-05-222015-06-15Bibliographically approved