Anilide Formation from Thioacids and Perfluoroaryl Azides
2015 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 80, no 9, 4392-4397 p.Article in journal (Refereed) Published
A metal-free method for fast and clean anilide formation from perfluoroaryl azide and thioacid is presented. The reaction proved highly efficient, displaying fast kinetics, high yield, and good chemoselectivity. The transformation was compatible with various solvents and tolerant to a wide variety of functional groups, and it showed high performance in polar protic/aprotic media, including aqueous buffer systems.
Place, publisher, year, edition, pages
2015. Vol. 80, no 9, 4392-4397 p.
Functional groups, Aqueous buffer, Chemical equations, Chemo-selectivity, Fast kinetics, High yield, Metal free, Polar protic, Thioacids
IdentifiersURN: urn:nbn:se:kth:diva-169279DOI: 10.1021/acs.joc.5b00240ISI: 000354004600016PubMedID: 25837012ScopusID: 2-s2.0-84928901913OAI: oai:DiVA.org:kth-169279DiVA: diva2:822364
QC 201506162015-06-162015-06-122015-09-03Bibliographically approved