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3D/2D Image Registration for Patient Positioning in Stereotactic Radiosurgery
KTH, School of Computer Science and Communication (CSC).
2015 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesisAlternative title
3D/2D bildregistrering för patientpositionering i stereotaktisk strålkirurgi (Swedish)
Abstract [en]

In the application of stereotactic radiosurgery for treatment of brain tumors it is imperative that patients are positioned with sub-millimetre accuracy so as to not damage surrounding healthy tissue during treatment.

We investigate how feasible the technique of digitally reconstructed radiographs is as a registration method for patient positioning in this type of high-accuracy application. In particular, since most registration methods based on said technique only rely on two simultaneous projection angles seldom reaching high enough accuracy, we consider any arbitrary amount and observe its effects on the registration accuracy. Three different approaches are considered for how multiple projections can be combined into one single metric.

The results seem to indicate that although computed tomography yields accuracies well within the boundaries for stereotactic radiosurgery, cone beam computed tomography in its current state does not. Possible reasons explaining the difference include problems with reconstruction artifacts in the model and inadequate metrics.

Abstract [sv]

Inom tillämpningen av stereotaktisk strålkirurgi för behandling av hjärntumörer är det absolut nödvändigt att patienter positioneras inom millimeternoggrannhet för att undvika skada hos närliggande vävnad vid behandling.

Vi undersöker hur trolig tekniken om digitaliserade återskapande röntgenbilder är som en registreringsmetod för patientpositionering i den här typen av mycket noggranna applikationer. Framförallt betraktas godtyckligt många projektionsvinklar och observerar dess effekt på registreringsnoggrannheten, eftersom de flesta tidigare presenterade registreringsmetoderna endast är baserade på två projektionsvinklar och sällan uppfyller det krav som ställs på noggrannhet. Tre olika tillvägagångssätt betraktas för hur flertalet projektionsvinklar kan kombineras till ett enda avståndsmått.

Resultaten verkar tyda på att datortomografi medför noggrannheter väl inom ramen för stereotaktisk strålkirurgi, medan konstråledatortomografi i sitt nuvarande tillstånd inte verkar göra detta. Anledningar till denna olikhet tros vara problem med rekonstruktionsartefakter i modellen och otillräckliga avståndsmått.

Place, publisher, year, edition, pages
2015.
Keyword [en]
3D/2D, Image Registration, Radiosurgery
National Category
Computer Science
Identifiers
URN: urn:nbn:se:kth:diva-170639OAI: oai:DiVA.org:kth-170639DiVA: diva2:839326
External cooperation
Elekta Instrument AB
Educational program
Master of Science in Engineering - Computer Science and Technology
Supervisors
Examiners
Available from: 2015-07-10 Created: 2015-07-02 Last updated: 2015-07-10Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
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