A smart catheter system for minimally invasive brain monitoring
2015 (English)In: Proceedings of the International Conference on Biomedical Electronics and Devices, SciTePress, 2015, 198-203 p.Conference paper (Refereed)
This paper demonstrates a smart catheter system with intracranial pressure (ICP) and temperature sensing capability which is designed for real-time monitoring in traumatic brain injury (TBI) therapy. It uses a single flexible catheter with a 1 mm (3 Fr) diameter that integrates electrodes and sophisticated silicon chip on flexible substrates, enabling multimodality monitoring of physiological signals. A micro-electromechanical-system (MEMS) catheter pressure sensor is mounted on the distal end. It can be used for detecting both pressure and temperature by different switch configurations, which minimizes the size of catheter and reduces the cost. The interconnects (signalling conductors) are printed on a bio-compatible flexible substrate, and the sensor is interfaced with an embedded electronic system at the far-end. The electronic system consists of analog front end with analog-to-digital converter (ADC), a microcontroller, and data interface to the hospital infrastructure with a graphical user interface (GUI). The overall smart catheter system achieves a pressure sensing root mean square error (RMSE) of ±1.5 mmHg measured from 20 mmHg to 300 mmHg above 1 atm and a temperature sensing RMSE of ±0.08°C measured from 32°C to 42°C. The sampling rate can be up to 10S/s. The in vivo performance is demonstrated in laboratory animals.
Place, publisher, year, edition, pages
SciTePress, 2015. 198-203 p.
Pressure, Real-time monitoring, Smart catheter, TBI, Temperature
Biomedical Laboratory Science/Technology
IdentifiersURN: urn:nbn:se:kth:diva-174732DOI: 10.5220/0005285501980203ISI: 000380546700031ScopusID: 2-s2.0-84936803084ISBN: 978-989-758-071-0OAI: oai:DiVA.org:kth-174732DiVA: diva2:860882
8th International Conference on Biomedical Electronics and Devices, BIODEVICES 2015; Lisbon; Portugal
QC 20151014. QC 201602122015-10-142015-10-072016-09-05Bibliographically approved