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Towards paper-based point of care affinity proteomics
KTH, School of Biotechnology (BIO), Proteomics and Nanobiotechnology.
KTH, School of Biotechnology (BIO), Proteomics and Nanobiotechnology.
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2014 (English)In: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, Chemical and Biological Microsystems Society , 2014, 64-66 p.Conference paper (Refereed)
Abstract [en]

Affinity-based methods such as protein microarrays have come to complement conventional mass/charge-based techniques for proteomic characterization of biological samples. Simultaneous measurement of hundreds or even thousands of serum biomarkers such as antibodies, antigens and other proteins may greatly improve the diagnostic accuracy in a variety of conditions such as autoimmune disorders, infections and several cancers. However, today's technologies for affinity proteomics are cumbersome, require expensive equipment and skilled operators. Here, we present two novel paper-based techniques developed in our lab that aim to bridge the gap between highly multiplexed affinity proteomics and point of care testing.

Place, publisher, year, edition, pages
Chemical and Biological Microsystems Society , 2014. 64-66 p.
Keyword [en]
Affinity proteomics, Gold nanoparticles, Paper, Point of care, Protein microarray, Antibodies, Bioassay, Biochips, Microarrays, Molecular biology, Affinity-proteomics, Autoimmune disorder, Expensive equipments, Point-of-care testing, Simultaneous measurement, Proteins
National Category
Medical Biotechnology
Identifiers
URN: urn:nbn:se:kth:diva-174810ScopusID: 2-s2.0-84941616748ISBN: 9780979806476OAI: oai:DiVA.org:kth-174810DiVA: diva2:881501
Conference
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, 26 October 2014 through 30 October 2014
Note

QC 20151210

Available from: 2015-12-10 Created: 2015-10-07 Last updated: 2015-12-10Bibliographically approved

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Chinnasamy, ThiruppathirajaGantelius, Jesper
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