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A facile approach toward multifunctional polyethersulfone membranes via in situ cross-linked copolymerization
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2015 (English)In: Journal of Biomaterials Science. Polymer Edition, ISSN 0920-5063, E-ISSN 1568-5624, Vol. 26, no 15, 1013-1034 p.Article in journal (Refereed) Published
Abstract [en]

In this study, multifunctional polyethersulfone (PES) membranes are prepared via in situ cross-linked copolymerization coupled with a liquid-liquid phase separation technique. Acrylic acid (AA) and N-vinylpyrrolidone (VP) are copolymerized in PES solution, and the solution is then directly used to prepare PES membranes. The infrared and X-ray photoelectron spectroscopy testing, scanning electron microscopy, and water contact angle measurements confirm the successful modification of pristine PES membrane. Protein adsorption, platelet adhesion, plasma recalcification time, and activated partial thromboplastin time assays convince that the modified PES membranes have a better biocompatibility than pristine PES membrane. In addition, the modified membranes showed good protein antifouling property and significant adsorption property of cationic dye. The loading of Ag nanoparticles into the modified membranes endows the composite membranes with antibacterial activity.

Place, publisher, year, edition, pages
Taylor & Francis, 2015. Vol. 26, no 15, 1013-1034 p.
Keyword [en]
facile, in situ cross-linked copolymerization, multifunctional, polyethersulfone membrane, Biocompatibility, Composite membranes, Copolymerization, Dyes, Hydrogels, Phase separation, Proteins, Scanning electron microscopy, Silver, X ray photoelectron spectroscopy, Activated partial thromboplastin time, Anti-bacterial activity, Liquid phase separation, Plasma recalcification time, Water contact angle measurement, Membranes, 1 vinyl 2 pyrrolidinone, acrylic acid, antifouling agent, nanocomposite, polyacrylic acid, polyethersulfone, povidone, protein, silver nanoparticle, water, adsorption, adult, antibacterial activity, anticoagulation, Article, blood compatibility, chemical parameters, contact angle, controlled study, drug delivery system, drug efficacy, fouling control, human, human cell, hydrophilicity, hydrophobicity, in situ cross linked copolymerization, infrared spectroscopy, liquid liquid phase separation, male, nanopharmaceutics, nonhuman, partial thromboplastin time, polymerization, priority journal, thrombocyte adhesion, time
National Category
Polymer Technologies
Identifiers
URN: urn:nbn:se:kth:diva-175102DOI: 10.1080/09205063.2015.1071929ISI: 000370283200003Scopus ID: 2-s2.0-84940449275OAI: oai:DiVA.org:kth-175102DiVA: diva2:882160
Note

QC 20151214, QC 20160318

Available from: 2015-12-14 Created: 2015-10-09 Last updated: 2016-03-18Bibliographically approved

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