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Consistent intensity inhomogeneity correction in water-fat MRI
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2015 (English)In: Journal of Magnetic Resonance Imaging, ISSN 1053-1807, E-ISSN 1522-2586, Vol. 42, no 2Article in journal (Refereed) Published
Abstract [en]

PURPOSE: To quantitatively and qualitatively evaluate the water-signal performance of the consistent intensity inhomogeneity correction (CIIC) method to correct for intensity inhomogeneities

METHODS: Water-fat volumes were acquired using 1.5 Tesla (T) and 3.0T symmetrically sampled 2-point Dixon three-dimensional MRI. Two datasets: (i) 10 muscle tissue regions of interest (ROIs) from 10 subjects acquired with both 1.5T and 3.0T whole-body MRI. (ii) Seven liver tissue ROIs from 36 patients imaged using 1.5T MRI at six time points after Gd-EOB-DTPA injection. The performance of CIIC was evaluated quantitatively by analyzing its impact on the dispersion and bias of the water image ROI intensities, and qualitatively using side-by-side image comparisons.

RESULTS: CIIC significantly ( P1.5T≤2.3×10-4,P3.0T≤1.0×10-6) decreased the nonphysiological intensity variance while preserving the average intensity levels. The side-by-side comparisons showed improved intensity consistency ( Pint⁡≤10-6) while not introducing artifacts ( Part=0.024) nor changed appearances ( Papp≤10-6).

CONCLUSION: CIIC improves the spatiotemporal intensity consistency in regions of a homogenous tissue type.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2015. Vol. 42, no 2
National Category
Radiology, Nuclear Medicine and Medical Imaging
Research subject
Medical Technology
URN: urn:nbn:se:kth:diva-179948DOI: 10.1002/jmri.24778PubMedID: 25355066ScopusID: 2-s2.0-84937570017OAI: diva2:890873

QC 20160113

Available from: 2016-01-05 Created: 2016-01-05 Last updated: 2016-01-13Bibliographically approved

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Smedby, Örjan
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Medical Image Processing and Visualization
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