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Evaluating Arterial and Plaque Elasticity with Shear Wave Elastography in an ex vivo Porcine Model
KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging. Karolinska Inst, Sweden.ORCID iD: 0000-0002-2487-7400
KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.ORCID iD: 0000-0002-9654-447X
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2015 (English)In: 2015 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), IEEE , 2015Conference paper (Refereed)Text
Abstract [en]

Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 +/- 0 kPa to 100 +/- 1 kPa and 81 +/- 2 kPa to 174 +/- 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

Place, publisher, year, edition, pages
IEEE , 2015.
Series
, IEEE International Ultrasonics Symposium, ISSN 1948-5719
Keyword [en]
Carotid Artery, Phase Velocity, Plaque Characterization, Shear Wave Elastography, Ultrasound
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-180170DOI: 10.1109/ULTSYM.2015.0120ISI: 000366045700426ScopusID: 2-s2.0-84962018816ISBN: 978-1-4799-8182-3OAI: oai:DiVA.org:kth-180170DiVA: diva2:893135
Conference
IEEE International Ultrasonics Symposium (IUS), OCT 21-24, 2015, Taipei, TAIWAN
Note

QC 20160112

Available from: 2016-01-12 Created: 2016-01-07 Last updated: 2016-01-12Bibliographically approved

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Widman, ErikMaksuti, EliraLarsson, Matilda
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