Ultrarapid synthesis of microbeads with tuneable surface probe density
2016 (English)In: Ultrarapid synthesis of microbeads with tuneable surface probe density, Shanghai, China: IEEE conference proceedings, 2016, Vol. 2016, 731-734 p.Conference paper (Refereed)
We present, for the first time, a simplified and ultrarapid (~ 1s) approach for synthesis of microbeads with thiol- functionalized surfaces as potential binding sites, whose density can be tuned according to the ratio of two components in the prepolymer. We verify the successful generation of microbeads and their tuneable surface density resulted from different prepolymer off-stoichiometric ratio. This novel approach can be used for bioassays that require rapid surface capture probe binding and customized probe density for suitable bioreactions.
Place, publisher, year, edition, pages
Shanghai, China: IEEE conference proceedings, 2016. Vol. 2016, 731-734 p.
, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), ISSN 1084-6999 ; 2016
microbeads, microfluidics, off-stoichiometry thiol-ene, OSTE
Medical and Health Sciences
Research subject Materials Science and Engineering
IdentifiersURN: urn:nbn:se:kth:diva-181779DOI: 10.1109/MEMSYS.2016.7421732ISI: 000381797300192ScopusID: 2-s2.0-84970996576ISBN: 978-150901973-1OAI: oai:DiVA.org:kth-181779DiVA: diva2:900116
29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016, Shanghai, China, 24 January 2016 through 28 January 2016
FunderStockholm County Council, 66673Swedish Childhood Cancer Foundation, 66673
QC 201610182016-02-032016-02-032016-10-18Bibliographically approved