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One-pot biocatalytic amine transaminase/acyl transferase cascade for aqueous formation of amides from aldehydes or ketones
KTH, School of Biotechnology (BIO), Industrial Biotechnology. (AlbaNova University Center)ORCID iD: 0000-0003-3073-5641
KTH, School of Biotechnology (BIO), Industrial Biotechnology. (AlbaNova University Center)
KTH, School of Biotechnology (BIO), Industrial Biotechnology. (AlbaNova University Center)ORCID iD: 0000-0002-2993-9375
KTH, School of Biotechnology (BIO), Industrial Biotechnology. (AlbaNova University Center)ORCID iD: 0000-0002-9577-832X
2016 (English)In: catalysis science & technology, ISSN 2044-4753, Vol. 6, 2897-2900 p.Article in journal (Refereed) PublishedText
Abstract [en]

An efficient one-pot one-step biocatalytic amine transaminase/acyl transferase cascade for the formation of amides from the corresponding aldehydes and ketones in aqueous solution has been developed. N-benzyl-2-methoxyacetamide has been synthesized utlilizing the developed cascade in conversions up to 97%. The cascade was also evaluated for the synthesis of chiral amides.

Place, publisher, year, edition, pages
Royal Society of Chemistry, 2016. Vol. 6, 2897-2900 p.
National Category
Biocatalysis and Enzyme Technology
Identifiers
URN: urn:nbn:se:kth:diva-185329DOI: 10.1039/C6CY00435KISI: 000375545600004ScopusID: 2-s2.0-84967261237OAI: oai:DiVA.org:kth-185329DiVA: diva2:920159
Note

QC 20160422

Available from: 2016-04-16 Created: 2016-04-16 Last updated: 2016-06-08Bibliographically approved

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Publisher's full textScopushttp://dx.doi.org/10.1039/C6CY00435K

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Land, HenrikHendil-Forssell, PeterMartinelle, MatsBerglund, Per
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