Lipase-catalyzed kinetic resolution of 3-phenyloxazolidin-2-one derivatives: Cascade O- and N-alkoxycarbonylations 2016 (English)In: Catalysis communications, ISSN 1566-7367, E-ISSN 1873-3905, Vol. 82, p. 11-15Article in journal (Refereed) Published

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Abstract [en]

A lipase-catalyzed, cascade kinetic resolution protocol has been established for the synthesis of 3-phenyloxazolidin-2-one derivatives with up to excellent enantioselectivities (95% ee). Candida antarctica lipase B showed high catalytic activity and stereoselectivity in sequential O- and N-alkoxycarbonylation processes.

Place, publisher, year, edition, pages

Elsevier, 2016. Vol. 82, p. 11-15

Keywords [en]

Asymmetric, synthesis, Candida antarctica lipase B, Cascade alkoxycarbonylation, Kinetic resolution, Oxazolidinone, Candida, Catalysis, Catalyst activity, Isomers, Yeast, Alkoxycarbonylation, Lipase-catalyzed, Oxazolidinones, Kinetics

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Chemical Sciences

Identifiers

URN: urn:nbn:se:kth:diva-186907DOI: 10.1016/j.catcom.2016.04.009ISI: 000377735500003Scopus ID: 2-s2.0-84964547460OAI: oai:DiVA.org:kth-186907DiVA, id: diva2:931187

Note

Funding Details: KTH, China Scholarship Council

QC 20160526

Available from: 2016-05-26 Created: 2016-05-16 Last updated: 2017-11-30Bibliographically approved

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Zhang, YangZhang, YanXie, ShengYan, MingdiRamström, Olof

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