Lipase-catalyzed kinetic resolution of 3-phenyloxazolidin-2-one derivatives: Cascade O- and N-alkoxycarbonylationsShow others and affiliations
2016 (English)In: Catalysis communications, ISSN 1566-7367, E-ISSN 1873-3905, Vol. 82, 11-15 p.Article in journal (Refereed) Published
Resource type
Text
Abstract [en]
A lipase-catalyzed, cascade kinetic resolution protocol has been established for the synthesis of 3-phenyloxazolidin-2-one derivatives with up to excellent enantioselectivities (95% ee). Candida antarctica lipase B showed high catalytic activity and stereoselectivity in sequential O- and N-alkoxycarbonylation processes.
Place, publisher, year, edition, pages
Elsevier, 2016. Vol. 82, 11-15 p.
Keyword [en]
Asymmetric, synthesis, Candida antarctica lipase B, Cascade alkoxycarbonylation, Kinetic resolution, Oxazolidinone, Candida, Catalysis, Catalyst activity, Isomers, Yeast, Alkoxycarbonylation, Lipase-catalyzed, Oxazolidinones, Kinetics
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-186907DOI: 10.1016/j.catcom.2016.04.009ISI: 000377735500003Scopus ID: 2-s2.0-84964547460OAI: oai:DiVA.org:kth-186907DiVA: diva2:931187
Note
Funding Details: KTH, China Scholarship Council
QC 20160526
2016-05-262016-05-162016-07-15Bibliographically approved