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Signal enhancement in ligand-receptor interactions using dynamic polymers at quartz crystal microbalance sensors
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Surface and Corrosion Science.
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2016 (English)In: The Analyst, ISSN 0003-2654, E-ISSN 1364-5528, Vol. 141, no 13, 3993-3996 p.Article in journal (Refereed) PublishedText
Abstract [en]

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly (acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

Place, publisher, year, edition, pages
2016. Vol. 141, no 13, 3993-3996 p.
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Organic Chemistry
URN: urn:nbn:se:kth:diva-190685DOI: 10.1039/c6an00735jISI: 000378942300006PubMedID: 27196531ScopusID: 2-s2.0-84976417964OAI: diva2:952612

QC 20160815

Available from: 2016-08-15 Created: 2016-08-12 Last updated: 2016-08-15Bibliographically approved

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Duner, GunnarRamstrom, Olof
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