Change search
ReferencesLink to record
Permanent link

Direct link
Pain rather than induced emotions and ICU sound increases skin conductance variability in healthy volunteers
Show others and affiliations
2016 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 60, no 8, 1111-1120 p.Article in journal (Refereed) Published
Abstract [en]

BackgroundAssessing pain in critically ill patients is difficult. Skin conductance variability (SCV), induced by the sympathetic response to pain, has been suggested as a method to identify pain in poorly communicating patients. However, SCV, a derivate of conventional skin conductance, could potentially also be sensitive to emotional stress. The purpose of the study was to investigate if pain and emotional stress can be distinguished with SCV. MethodsIn a series of twelve 1-min sessions with SCV recording, 18 healthy volunteers were exposed to standardized electric pain stimulation during blocks of positive, negative, or neutral emotion, induced with pictures from the International Affective PictureSystem (IAPS). Additionally, authentic intensive care unit (ICU) sound was included in half of the sessions. All possible combinations of pain and sound occurred in each block of emotion, and blocks were presented in randomized order. ResultsPain stimulation resulted in increases in the number of skin conductance fluctuations (NSCF) in all but one participant. During pain-free baseline sessions, the median NSCF was 0.068 (interquartile range 0.013-0.089) and during pain stimulation median NSCF increased to 0.225 (interquartile range 0.146-0.3175). Only small increases in NSCF were found during negative emotions. Pain, assessed with the numeric rating scale, during the sessions with pain stimulation was not altered significantly by other ongoing sensory input. ConclusionIn healthy volunteers, NSCF appears to reflect ongoing autonomous reactions mainly to pain and to a lesser extent, reactions to emotion induced with IAPS pictures or ICU sound.

Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Inc., 2016. Vol. 60, no 8, 1111-1120 p.
Keyword [en]
Intensive-Care-Unit, Postoperative Pain, Scale, Responses, Stimuli, Tool, Validation, Anesthesia, Management, Agitation
National Category
Anesthesiology and Intensive Care
URN: urn:nbn:se:kth:diva-192383DOI: 10.1111/aas.12751ISI: 000380960400010PubMedID: 27465523ScopusID: 2-s2.0-84982861764OAI: diva2:968791

QC 20160912

Available from: 2016-09-12 Created: 2016-09-12 Last updated: 2016-09-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Alvarsson, Jesper
By organisation
Marcus Wallenberg Laboratory MWL
In the same journal
Acta Anaesthesiologica Scandinavica
Anesthesiology and Intensive Care

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 1 hits
ReferencesLink to record
Permanent link

Direct link