SHEAR WAVE ELASTOGRAPHY QUANTIFIES STIFFNESS IN EX VIVO PORCINEARTERY WITH STIFFENED ARTERIAL REGION
Number of Authors: 6
2016 (English)In: Ultrasound in Medicine and Biology, ISSN 0301-5629, E-ISSN 1879-291X, Vol. 42, no 10, 2423-2435 p.Article in journal (Refereed) Published
Five small porcine aortas were used as a human carotid artery model, and their stiffness was estimatedusing shear wave elastography (SWE) in the arterial wall and a stiffened artery region mimicking a stiff plaque. Tooptimize the SWE settings, shear wave bandwidth was measured with respect to acoustic radiation force pushlength and number of compounded angles used for motion detection with plane wave imaging. The mean arterialwall and simulated plaque shear moduli varied from 41 ± 5 to 97 ± 10 kPa and from 86 ± 13 to 174 ± 35 kPa, respectively,over the pressure range 20–120 mmHg. The results revealed that a minimum bandwidth of approximately1500 Hz is necessary for consistent shear modulus estimates, and a high pulse repetition frequency using no imagecompounding is more important than a lower pulse repetition frequency with better image quality when estimatingarterial wall and plaque stiffness using SWE.
Place, publisher, year, edition, pages
2016. Vol. 42, no 10, 2423-2435 p.
Artery, Arteriosclerosis, Atherosclerosis, Elasticity, Ex vivo, Plaque, Phase velocity, Shear wave elastography, Ultrasound
Medical Image Processing
Research subject Medical Technology
IdentifiersURN: urn:nbn:se:kth:diva-192857OAI: oai:DiVA.org:kth-192857DiVA: diva2:972538
QC 201609212016-09-212016-09-212016-09-21Bibliographically approved