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  • 1. Beronius, Anna
    et al.
    Rudén, Christina
    KTH, School of Architecture and the Built Environment (ABE), Philosophy.
    Håkansson, Helen
    Hanberg, Annika
    Risk to all or none? A comparative analysis of controversies in the health risk assessment of Bisphenol A2010In: Reproductive Toxicology, ISSN 0890-6238, E-ISSN 1873-1708, Vol. 29, no 2, p. 132-146Article in journal (Refereed)
    Abstract [en]

    Bisphenol A (BPA) is an endocrine disruptor for which health risk assessment has proven controversial. Conclusions regarding health risks of BPA vary between assessments from "there is no risk to any part of the population" to "there is risk to the entire population". We have carried out a literature study investigating what might be the scientific and/or policy-related reasons for these differences. Ten risk assessments for BPA were scrutinized and several factors were compared between assessments, including estimations of exposure levels, identification of critical study and NOAEL, assessment factors and significance attributed to reports of low-dose effects. Differences in conclusions were mainly influenced by the evaluation of low-dose effects and the uncertainties surrounding the significance of these data for health risk assessment. The results illustrate the impact of differences in risk assessment policy and expert judgment on the risk assessment process and highlight the importance of transparency in this process.

  • 2.
    Rudén, Christina
    et al.
    KTH, School of Architecture and the Built Environment (ABE), Philosophy and History of Technology, Philosophy.
    Hansson, Sven Ove
    KTH, School of Architecture and the Built Environment (ABE), Philosophy and History of Technology, Philosophy.
    Comment on: "A retrospective analysis of the two-generation study: What is the added value of the second generation?" by G. Janer, B.C. Hakkert, W. Slob, T. Vermeire, A.H. Piersma Reprod. Toxicol. 24 (2007) 97-1022008In: Reproductive Toxicology, ISSN 0890-6238, E-ISSN 1873-1708, Vol. 25, no 4, p. 397-405Article in journal (Refereed)
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