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  • 1.
    Wolffsohn, James S.
    et al.
    Aston Univ, Ophthalm Res Grp, Birmingham, W Midlands, England..
    Kollbaum, Pete S.
    Indiana Univ, Sch Optometry, Bloomington, IN USA..
    Berntsen, David A.
    Univ Houston, Coll Optometry, Ocular Surface Inst, Houston, TX USA..
    Atchison, David A.
    Queensland Univ Technol, Sch Optometry & Vis Sci, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia..
    Benavente, Alexandra
    SUNY Coll Optometry, New York, NY 10036 USA..
    Bradley, Arthur
    Indiana Univ, Sch Optometry, Bloomington, IN USA..
    Buckhurst, Hetal
    Plymouth Univ, Sch Hlth Profess, Peninsula Allied Hlth Ctr, Plymouth, Devon, England..
    Collins, Michael
    Queensland Univ Technol, Sch Optometry & Vis Sci, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia..
    Fujikado, Takashi
    Osaka Univ, Grad Sch Med, Dept Appl Visual Sci, Osaka, Japan..
    Hiraoka, Takahiro
    Univ Tsukuba, Dept Ophthalmol, Fac Med, Ibaraki, Japan..
    Hirota, Masakazu
    Osaka Univ, Grad Sch Med, Dept Appl Visual Sci, Osaka, Japan..
    Jones, Debbie
    Univ Waterloo, Sch Optometry & Vis Sci, Waterloo, ON, Canada..
    Logan, Nicola S.
    Aston Univ, Ophthalm Res Grp, Birmingham, W Midlands, England..
    Lundström, Linda
    KTH, School of Engineering Sciences (SCI), Applied Physics, Biomedical and X-ray Physics.
    Torii, Hidemasa
    Keio Univ, Sch Med, Dept Ophthalmol, Tokyo, Japan..
    Read, Scott A.
    Queensland Univ Technol, Sch Optometry & Vis Sci, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia..
    Naidoo, Kovin
    Univ KwaZulu Natal, African Vis Res Inst, Durban, South Africa..
    IMI - Clinical Myopia Control Trials and Instrumentation Report2019In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 60, no 3, p. M132-M160Article in journal (Refereed)
    Abstract [en]

    The evidence-basis based on existing myopia control trials along with the supporting academic literature were reviewed; this informed recommendations on the outcomes suggested from clinical trials aimed at slowing myopia progression to show the effectiveness of treatments and the impact on patients. These outcomes were classified as primary (refractive error and/or axial length), secondary (patient reported outcomes and treatment compliance), and exploratory (peripheral refraction, accommodative changes, ocular alignment, pupil size, outdoor activity/lighting levels, anterior and posterior segment imaging, and tissue biomechanics). The currently available instrumentation, which the literature has shown to best achieve the primary and secondary outcomes, was reviewed and critiqued. Issues relating to study design and patient selection were also identified. These findings and consensus from the International Myopia Institute members led to final recommendations to inform future instrumentation development and to guide clinical trial protocols.

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