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  • 1.
    Abourraja, Mohamed Nezar
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Marzano, Luca
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Boodaghian Asl, Arsineh
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Lethvall, Sven
    Uppsala University Hospital,Uppsala,Sweden.
    Falk, Nina
    Uppsala University Hospital,Uppsala,Sweden.
    A Data-Driven Discrete Event Simulation Model to Improve Emergency Department Logistics2022Ingår i: Proceedings of the 2022 Winter Simulation Conference, Institute of Electrical and Electronics Engineers (IEEE) , 2022Konferensbidrag (Refereegranskat)
    Abstract [en]

    Demands for health care are becoming overwhelming for healthcare systems around the world regarding theavailability of resources, particularly, in emergency departments (EDs) that are continuously open and mustserve immediately any patient who comes in. Efficient management of EDs and their resources is requiredmore than ever. This could be achieved either by optimizing resource utilization or by the improvement ofhospital layout. This paper investigates, through data-driven simulation alternative designs of workflowsand layouts to operate the ED of the Uppsala University Hospital in Sweden. Results are analyzed tounderstand the requirements across the hospital for reduced waiting times in the ED. The main observationrevealed that introducing a new ward dedicated to patients having complex diagnoses with a capacity ofless than 20 beds leads to lower waiting times. Furthermore, the use of data-mining was of great help inreducing the efforts of building the simulation model.

  • 2.
    Azhari, Mohammad
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Raghothama, Jayanth
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    A Design and Implementation of Interactive Visualizations and Simulation in Transportation2014Ingår i: The Shift from Teaching to Learning: Individual, Collective and Organizational Learning Through Gaming Simulation: Proceedings of the 45th Conferenceof the International Simulation and Gaming Association, 2014Konferensbidrag (Refereegranskat)
    Abstract [en]

    Transportation Planners have a long history of using Geographical Information Systems, Simulation Models and Visualizations for decision support. A frame-work that integrates all three can provide enhanced decision support, opportuni-ties for training and planning future scenarios. In the current paper, we describe the concept of such a framework and the first steps toward its development.

  • 3.
    Balogh, Dora B.
    et al.
    Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.
    Hudelist, Gernot
    Department of Gynecology, Center for Endometriosis, Hospital St. John of God, Vienna, Austria; Rudolfinerhaus Private Clinic and Campus, Vienna, Austria.
    Bļizņuks, Dmitrijs
    Department of Computer Control and Computer Networks, Riga Technical University, Riga, Latvia.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Becker, Christian M.
    Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
    Horace, Roman
    Franco-European Multidisciplinary Endometriosis Institute (IFEMEndo), Clinique Tivoli-Ducos, Bordeaux, France, Clinique Tivoli-Ducos.
    Krentel, Harald
    Department of Obstetrics, Gynecology, Gynecologic Oncology and Senology, Bethesda Hospital Duisburg, Duisburg, Germany.
    Horne, Andrew W.
    Centre for Reproductive Health, University of Edinburgh, Institute of Inflammation and Repair, Edinburgh, United Kingdom.
    Bourdel, Nicolas
    Department of Surgical Gynecology, University of Clermont Auvergne, Clermont-Ferrand, France.
    Marki, Gabriella
    MedEnd Institute, Budapest, Hungary.
    Tomassetti, Carla
    Leuven University Endometriosis Center of Expertise, Leuven University Fertility Center, Department of Obstetrics and Gynecology, UZ Gasthuisberg, Leuven, Belgium.
    Kirk, Ulrik Bak
    Department of Public Health, Aarhus University, Aarhus, Denmark; Research Unit for General Practice, Aarhus, Denmark.
    Acs, Nandor
    Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.
    Bokor, Attila
    Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.
    FEMaLe: The use of machine learning for early diagnosis of endometriosis based on patient self-reported data—Study protocol of a multicenter trial2024Ingår i: PLOS ONE, E-ISSN 1932-6203, Vol. 19, nr 5 May, artikel-id e0300186Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Introduction Endometriosis is a chronic disease that affects up to 190 million women and those assigned female at birth and remains unresolved mainly in terms of etiology and optimal therapy. It is defined by the presence of endometrium-like tissue outside the uterine cavity and is commonly associated with chronic pelvic pain, infertility, and decreased quality of life. Despite the availability of various screening methods (e.g., biomarkers, genomic analysis, imaging techniques) intended to replace the need for invasive surgery, the time to diagnosis remains in the range of 4 to 11 years. Aims This study aims to create a large prospective data bank using the Lucy mobile health application (Lucy app) and analyze patient profiles and structured clinical data. In addition, we will investigate the association of removed or restricted dietary components with quality of life, pain, and central pain sensitization. Methods A baseline and a longitudinal questionnaire in the Lucy app collects real-world, self-reported information on symptoms of endometriosis, socio-demographics, mental and physical health, economic factors, nutritional, and other lifestyle factors. 5,000 women with confirmed endometriosis and 5,000 women without diagnosed endometriosis in a control group will be enrolled and followed up for one year. With this information, any connections between recorded symptoms and endometriosis will be analyzed using machine learning. Conclusions We aim to develop a phenotypic description of women with endometriosis by linking the collected data with existing registry-based information on endometriosis diagnosis, healthcare utilization, and big data approach. This may help to achieve earlier detection of endometriosis with pelvic pain and significantly reduce the current diagnostic delay. Additionally, we may identify dietary components that worsen the quality of life and pain in women with endometriosis, upon which we can create real-world data-based nutritional recommendations.

  • 4.
    Boodaghian Asl, Arsineh
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    A hybrid modeling approach to simulate complex systems and classify behaviors2024Ingår i: NETWORK MODELING AND ANALYSIS IN HEALTH INFORMATICS AND BIOINFORMATICS, ISSN 2192-6662, Vol. 13, nr 1, artikel-id 9Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Many important systems, both natural and artificial, are complex in nature, and models and simulations are one of the main instruments to study them. In this paper, we present an approach where a complex social system is represented at a high level of abstraction as a network, thereby addressing several challenges such as quantification, intervention, adaptation and validation. The network represents the factors that influence the mental health and wellbeing in children and young people. In this article, we present an approach that links a system dynamics simulation to simulate the network and ranking algorithms to measure the vertices' behaviors. The network is enhanced by adding edge strengths in the form of correlations between vertices (established through literature). Such an approach allows us to exploit the network structure to qualify and quantify the vertices of the network, to overlay different processes over the network topology, to add and remove new vertices, and therefore interact dynamically. This in turn allows for the qualification of vertices' importance and network resilience. System dynamics simulation allows for policy analysis, where different scenarios are analyzed by stimulating a set of vertices and the effect over the network is observed. This approach allows for an abstract, flexible, yet comprehensive way of analyzing a complex social network at any scale.

  • 5.
    Boodaghian Asl, Arsineh
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Simulation and Model Validation for Mental Health Factors Using a Multi-Methodology Hybrid Approach2021Ingår i: Proceedings - Winter Simulation Conference, Institute of Electrical and Electronics Engineers Inc. , 2021Konferensbidrag (Refereegranskat)
    Abstract [en]

    To promote policy analysis and decision-making in mental health and well-being, simulations are used to scrutinize causal maps and provide policymakers reasonable evidence. This paper proposes and illustrates a multi-methodology hybrid approach by building a hierarchy of models, moving from a systems dynamics model to a simulation based on PageRank to quantify and assess a complex mental health map. The motives are: (1) to aid scenario analysis and comparison for possible policy interventions, (2) to quantify and validate mental health factors, and (3) to gain new insights into the core and confounding factors that affect mental health. The results indicate that the approach identifies factors that cause significant and frequent variation on mental health. Furthermore, validation confirms PageRank accuracy and detects minor fluctuations and variation in model's output behavior.

  • 6.
    Boodaghian Asl, Arsineh
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Using pageRank and social network analysis to specify mental health factors2021Ingår i: Proceedings of the Design Society: 23rd International Conference on Engineering Design, ICED 2021,, Cambridge University Press (CUP) , 2021, Vol. 1, s. 3379-3388Konferensbidrag (Refereegranskat)
    Abstract [en]

    Various factors influence mental well-being, and span individual, social and familial levels. These factors are connected in many ways, forming a complex web of factors and providing pathways for developing programs to improve well-being and for further research. These factors can be studied individually using traditional methods and mapped together to be analyzed holistically from a complex system perspective. This study provides a novel approach using PageRank and social network analysis to understand such maps. The motives are: (1) to realize the most influential factors in such complex networks, (2) to understand factors that influence variations from different network aspects. A previously developed map for children's mental well-being was adopted to evaluate the approach. To achieve our motives, we have developed an approach using PageRank and Social Network Analysis. The results indicate that regardless of the network scale, two key factors called "Quantity and Quality of Relationships" and "Advocacy" can influence children's mental well-being significantly. Moreover, the divergence analysis reveals that one factor, "Recognition/Value Placed on well-being at School" causes a wide range of diffusion throughout the system.

  • 7.
    Darwich, Adam S.
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Bostroem, Anne-Marie
    Karolinska Inst, Div Nursing, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.;Karolinska Univ Hosp, Theme Inflammat & Aging, Huddinge, Sweden.;Stockholms Sjukhem, Res & Dev Unit, Stockholm, Sweden..
    Guidetti, Susanne
    Karolinska Inst, Div Occupat Hlth, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden.;Karolinska Univ Hosp, Med Unit Occupat Therapy & Physiotherapy, Theme Womens Hlth & Allied Profess, Stockholm, Sweden..
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Investigating the Connections Between Delivery of Care, Reablement, Workload, and Organizational Factors in Home Care Services: Mixed Methods Study2023Ingår i: JMIR Human Factors, E-ISSN 2292-9495, Vol. 10, artikel-id e42283Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Home care is facing increasing demand due to an aging population. Several challenges have been identified in the provision of home care, such as the need for support and tailoring support to individual needs. Goal-oriented interventions, such as reablement, may provide a solution to some of these challenges. The reablement approach targets adaptation to disease and relearning of everyday life skills and has been found to improve health-related quality of life while reducing service use.Objective: The objective of this study is to characterize home care system variables (elements) and their relationships (connections) relevant to home care staff workload, home care user needs and satisfaction, and the reablement approach. This is to examine the effects of improvement and interventions, such as the person-centered reablement approach, on the delivery of home care services, workload, work-related stress, home care user experience, and other organizational factors. The main focus was on Swedish home care and tax-funded universal welfare systems.Methods: The study used a mixed methods approach where a causal loop diagram was developed grounded in participatory methods with academic health care science research experts in nursing, occupational therapy, aging, and the reablement approach. The approach was supplemented with theoretical models and the scientific literature. The developed model was verified by the same group of experts and empirical evidence. Finally, the model was analyzed qualitatively and through simulation methods.Results: The final causal loop diagram included elements and connections across the categories: stress, home care staff, home care user, organization, social support network of the home care user, and societal level. The model was able to qualitatively describe observed intervention outcomes from the literature. The analysis suggested elements to target for improvement and the potential impact of relevant studied interventions. For example, the elements "workload" and "distress" were important determinants of home care staff health, provision, and quality of care.Conclusions: The developed model may be of value for informing hypothesis formulation, study design, and discourse within the context of improvement in home care. Further work will include a broader group of stakeholders to reduce the risk of bias. Translation into a quantitative model will be explored.

  • 8.
    Hauge, Jannicke
    et al.
    KTH. BIBA, Bremer Institut für Produktion und Logistik an der Universität Bremen, Germany.
    Carretero, Ramos Miguel
    KTH.
    Kodjabachian, J.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Raghothama, Jayanth
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Duqueroie, B.
    Protoworld: a simulation based gaming environment to model and plan urban mobility2016Ingår i: 4th International Conference on Games and Learning Alliance, GALA 2015, Springer, 2016, s. 393-400Konferensbidrag (Refereegranskat)
    Abstract [en]

    This workshop will offer the participants the opportunity to explore and test a gaming environment integrating simulation data from different sources. The participants will model and play different mobility options for five European cities. The ProtoWorld solution integrates different simulations and street maps in Unity and allows a playful experience in urban mobility planning. The software will be available for the participants also after the workshop for further experimentation.

  • 9.
    Hellstrand, Mikaela
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Kornevs, Maksims
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Tensions between real-world practices and the digitalization paradigm for data-driven services in eldercare: observations from an ethnographic study in Sweden2024Ingår i: BMC Geriatrics, E-ISSN 1471-2318, Vol. 24, nr 1, artikel-id 98Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: The implementation of a data-driven approach within the health care system happens in a rapid pace; including in the eldercare sector. Within Swedish eldercare, data-driven health approach is not yet widely implemented. In the specific context of long-term care for older adults, quality of care is as much determined by how social care is being performed as it is by what kind medical care that is provided. In particular, relational aspects have been proven to have a crucial influence on the experience of quality of care for the actors involved. Drawing on ethnographic material collected at a Swedish nursing home, this paper explores in what way the relational aspects of care could potentially become affected by the increased use of a data-driven health approach. Methods: An ethnographic approach was adopted in order to investigate the daily care work at a long-term care facility as it unfolded. Fieldwork was conducted at a somatic ward in a Swedish long-term care facility over 4 months (86 h in total), utilizing the methods of participant observation, informal interviews and document analysis. The material was analyzed iteratively throughout the entire research process adopting thematic analysis. Results: Viewing our ethnographic material through an observational lense problematising the policy discourse around data-driven health approach, two propositions were developed. First, we propose that relational knowledge risk becoming less influential in shaping everyday care, when moving to a data-driven health approach. Second, we propose that quality of care risk becoming more directed on quality of medical care at the expense of quality of life. Conclusion: While the implementation of data-driven health approach within long-term care for older adults is not yet widespread, the general development within health care points towards a situation in which this will become reality. Our study highlights the importance of taking the relational aspects of care into consideration, both during the planning and implementation phase of this process. By doing this, the introduction of a data-driven health approach could serve to heighten the quality of care in a way which supports both quality of medical care and quality of life.

  • 10.
    Marzano, Luca
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Dan, A.
    Karolinska Inst, Stockholm, Sweden..
    Tendler, S.
    Karolinska Inst, Stockholm, Sweden..
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    De Petris, L.
    Karolinska Inst, Stockholm, Sweden..
    Lewensohn, R.
    Karolinska Inst, Stockholm, Sweden..
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    A Comparative Analysis between Real-World Data and Clinical Trials to Evaluate Differences in Outcomes for SCLC Patients2023Ingår i: Journal of Thoracic Oncology, ISSN 1556-0864, E-ISSN 1556-1380, Vol. 18, nr 11, s. S697-S697Artikel i tidskrift (Övrigt vetenskapligt)
  • 11.
    Marzano, Luca
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Sven, Lethvall
    Uppsala University Hospital, Uppsala, Sweden.
    Falk, Nina
    Uppsala University Hospital, Uppsala, Sweden.
    Bodeby, Patrik
    Uppsala University Hospital, Uppsala, Sweden.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Diagnosing an overcrowded emergency department from its Electronic Health Records2024Ingår i: Scientific Reports, E-ISSN 2045-2322, Vol. 14, nr 1, artikel-id 9955Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Emergency department overcrowding is a complex problem that persists globally. Data of visits constitute an opportunity to understand its dynamics. However, the gap between the collected information and the real-life clinical processes, and the lack of a whole-system perspective, still constitute a relevant limitation. An analytical pipeline was developed to analyse one-year of production data following the patients that came from the ED (n = 49,938) at Uppsala University Hospital (Uppsala, Sweden) by involving clinical experts in all the steps of the analysis. The key internal issues to the ED were the high volume of generic or non-specific diagnoses from non-urgent visits, and the delayed decision regarding hospital admission caused by several imaging assessments and lack of hospital beds. Furthermore, the external pressure of high frequent re-visits of geriatric, psychiatric, and patients with unspecified diagnoses dramatically contributed to the overcrowding. Our work demonstrates that through analysis of production data of the ED patient flow and participation of clinical experts in the pipeline, it was possible to identify systemic issues and directions for solutions. A critical factor was to take a whole systems perspective, as it opened the scope to the boundary effects of inflow and outflow in the whole healthcare system.

  • 12.
    Marzano, Luca
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Tendler, Salomon
    Department of Oncology‐Pathology Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital Stockholm Sweden.
    Dan, Asaf
    Department of Oncology‐Pathology Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital Stockholm Sweden.
    Lewensohn, Rolf
    Department of Oncology‐Pathology Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital Stockholm Sweden.
    De Petris, Luigi
    Department of Oncology‐Pathology Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital Stockholm Sweden.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    A novel analytical framework for risk stratification of real‐world data using machine learning: A small cell lung cancer study2022Ingår i: Clinical and Translational Science, ISSN 1752-8054, E-ISSN 1752-8062, Vol. 15, nr 10, s. 2437-2447Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In recent studies, small cell lung cancer (SCLC) treatment guidelines based on Veterans’ Administration Lung Study Group limited/extensive disease staging and resulted in broad and inseparable prognostic subgroups. Evidence suggests that the eight versions of tumor, node, and metastasis (TNM) staging can play an important role to address this issue. The aim of the present study was to improve the detection of prognostic subgroups from a real-word data (RWD) cohort of patients and analyze their patterns using a development pipeline with thoracic oncologists and machine learning methods. The method detected subgroups of patients informing unsupervised learning (partition around medoids) including the impact of covariates on prognosis (Cox regression and random survival forest). An analysis was carried out using patients with SCLC (n = 636) with stage IIIA–IVB according to TNM classification. The analysis yielded k = 7 compacted and well-separated clusters of patients. Performance status (Eastern Cooperative Oncology Group-Performance Status), lactate dehydrogenase, spreading of metastasis, cancer stage, and CRP were the baselines that characterized the subgroups. The selected clustering method outperformed standard clustering techniques, which were not capable of detecting meaningful subgroups. From the analysis of cluster treatment decisions, we showed the potential of future RWD applications to understand disease, develop individualized therapies, and improve healthcare decision making.

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  • 13.
    Marzano, Luca
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Dan, Asaf
    Department of Oncology-Pathology, Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden.
    Tendler, Salomon
    Department of Oncology-Pathology, Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden.
    De Petris, Luigi
    Department of Oncology-Pathology, Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden.
    Lewensohn, Rolf
    Department of Oncology-Pathology, Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Darwich, Adam S.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Application of Process Mining for Modelling Small Cell Lung Cancer Prognosis2023Ingår i: Studies in Health Technology and Informatics, ISSN 0926-9630, E-ISSN 1879-8365, Vol. 302, s. 18-22Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Process mining is a relatively new method that connects data science and process modelling. In the past years a series of applications with health care production data have been presented in process discovery, conformance check and system enhancement. In this paper we apply process mining on clinical oncological data with the purpose of studying survival outcomes and chemotherapy treatment decision in a real-world cohort of small cell lung cancer patients treated at Karolinska University Hospital (Stockholm, Sweden). The results highlighted the potential role of process mining in oncology to study prognosis and survival outcomes with longitudinal models directly extracted from clinical data derived from healthcare.

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  • 14.
    Meijer, Sebastiaan
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Olejniczak, Karol
    Institute of Social Sciences, SWPS University of Social Sciences and Humanities, Warsaw, Poland.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Public Policy and Engineering Systems Synergy2022Ingår i: Handbook of Engineering Systems Design / [ed] Maier, A., Oehmen, J., Vermaas, P.E., Springer Nature , 2022, s. 987-1010Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [en]

    Engineering systems cannot be seen separate from the context they work in. Increasing complexity of society makes that larger systems no longer just concern technical aspects but include social and even societal aspects. Particularly, the societal aspects can be subject to public policy as a part of engineering systems design. This chapter provides a discussion of the nature of public policy and the role it plays in engineering systems, as well as the role that engineering systems methods play for public policy design. The mutual relationship is positioned in a historic overview, where particularly the role of participatory methods has grown over time to capture human complex thinking in a world dominated by mathematic modelling approaches. It positions engineering systems to encompass public policy as an integral part of design, so that the traditional divide between engineering and societal contexts can be bridged.

  • 15.
    Meijer, Sebastiaan
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Trafik och logistik.
    Raghothama, Jayanth
    King, Robin
    Disentangling the complexity of India’s agricultural sector2012Ingår i: APSTRACT: Applied Studies In Agribusiness And Commerce, ISSN 1789-221X, E-ISSN 1789-7874, Vol. 06, nr 1-2, s. 35-43Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Agricultural policies in India directly impact the livelihoods of close to two thirds of India’s population. Through policies, thegovernment manages food security, urban and rural poverty, energy, and infrastructure, among others. Given the current state of India’sgovernance, the connection between policy making and its results in society becomes a key issue for research. This paper presents a game foruse as a research instrument. The game can facilitate research into the policy making process at various levels of the government in India. Thedesign is intended to understand the complexity of the institutional arrangement that defines and implements agricultural policies. The gameintegrates with other games that simulate other aspects of the agricultural system in India. The paper presents the verification and validationcycles followed, and identifies further steps for field validation.

  • 16.
    Raghothama, Jayanth
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Integrating Computational and Participatory Simulations for Design in Complex Systems2017Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    The understanding and conceptualization of cities and its constituent systems such as transportation and healthcare as open and complex is shifting the debates around the technical and communicative rationales of planning. Viewing cities in a holistic manner presents methodological challenges, where our understanding of complexity is applied in a tangible fashion to planning processes. Bridging the two rationales in the tools and methodologies of planning is necessary for the emergence of a 'non-linear rationality' of planning, one that accounts for and is premised upon complexity. Simulations representing complex systems provide evidence and support for planning, and have the potential to serve as an interface between the more abstract and political decision making and the material city systems.

    Moving beyond current planning methods, this thesis explores the role of simulations in planning. Recognizing the need for holistic representations, the thesis integrates multiple disparate simulations into a holistic whole achieving complex representations of systems. These representations are then applied and studied in an interactive environment to address planning problems in different contexts. The thesis contributes an approach towards the development of complex representations of systems; improvements on participatory methods to integrate computational simulations; a nuanced understanding of the relative value of simulation constructs; technologies and frameworks that facilitate the easy development of integrated simulations that can support participatory planning processes.

    The thesis develops contributions through experiments which involved problems and stakeholders from real world systems. The approach towards development of integrated simulations is realized in an open source framework. The framework creates computationally efficient, scalable and interactive simulations of complex systems, which used in a participatory manner delivers tangible plans and designs.

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  • 17.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH).
    Azhari, Mohammed
    KTH, Skolan för teknik och hälsa (STH).
    Carretero, Miguel Ramos
    KTH, Skolan för teknik och hälsa (STH).
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH).
    Architectures for distributed, interactive and integrated traffic simulations2015Ingår i: Models and Technologies for Intelligent Transportation Systems (MT-ITS), 2015 International Conference on, IEEE , 2015, s. 387-394Konferensbidrag (Refereegranskat)
    Abstract [en]

    The rapid development of Intelligent Transport Systems has created new objectives and requirements for traffic simulation models. The development of visualization, procedural modeling, decision support requirements mean that simulation models need to satisfy different requirements. The chapter presents methods and tools to create distribute, integrated and interactive transport simulations, to enable the holistic exploration of complex transport systems, to test different strategies for monitoring and control and for training personnel. The integrated simulation is built leveraging gaming technologies, integrating commercial or off-the-shelf simulations using methods from distributed simulation and procedural modeling techniques.

  • 18.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Baalsrud Hauge, Jannicke
    KTH, Skolan för industriell teknik och management (ITM), Hållbar produktionsutveckling (ML).
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Curating Player Experience Through Simulations in City Games2022Ingår i: Urban Planning, E-ISSN 2183-7635, Vol. 7, nr 2, s. 253-263Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The use of games as a method for planning and designing cities is often associated with visualisation, from simplistic to immersive environments. They can also include complex and sophisticated models which provide an evidence base. The use of such technology as artefacts, aids, or mechanics curates the player experience in different and very often subtle ways, influencing how we engage with (simulated) urban phenomena, and, therefore, how the games can be used. In this article, we aim to explore how different aspects of technology use in city games influence the player experience and game outcomes. The article describes two games built upon the same city gaming framework, played with professionals in Rome and Haifa, respectively. Using a mixed-method, action research approach, the article examines how the high-tech, free form single-player games elicit the mental models of players (traffic controllers and planners in both cases). Questionnaires and the players' reflections on the gameplay, models used, and outcomes have been transcribed and analysed. Observations and results point to several dimensions that are critical to the outcomes of digital city games. Agency, exploration, openness, complexity, and learning are aspects that are strongly influenced by technology and models, and in turn, determine the outcomes of the game. City games that balance these aspects unlock player expertise to better understand the game dynamics and enable their imagination to better negotiate and resolve conflicts in design and planning.

  • 19.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Baalsrud Hauge, Jannicke
    KTH, Skolan för industriell teknik och management (ITM).
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Evaluating City Operations Design using Interactive SimulationsIngår i: Journal Simulation & Gaming, ISSN 1046-8781, E-ISSN 1552-826XArtikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background. Games and simulations are evaluated for serving different functions, such as learning, design, communication and collaboration. Research on the relationship between the constructs of games and their outcomes can provide insights on the design of future games, to steer towards particular outcomes.

     

    Aim. The article aims to relate the constructs of two high fidelity, high tech and free form games to a conceptual evaluation framework, to better understand the relationships between constructs such as fidelity, validity and the functions a game is meant to serve.

     

    Method. The games are built for designing operational procedures for city management. The games are built using the ProtoWorld framework, and simulate the cities of Rome and Haifa through the integration of simulations. The framework enables run time interaction and intervention within the simulated city, such that players can manage and design procedures for their cities through a large scale, realistic simulation system. Controllers from both cities play the games for their respective cities, and attempt to design and manage their simulated cities. As experts on the system, their reflections on the use of such tools in their planning practice and the outcomes of the game sessions are analyzed to evaluate the games and game sessions.

     

    Results. Results point to the free form nature of the game enabling the design of tangible outcomes, which can be immediately validated and implemented in practice. The high fidelity nature of the simulation restricts facilitation, but enhances the players’ ability to comprehend complexity. The agency of the players enables their identification with the simulation, but restricts their creativity in the game. 

  • 20.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Hanchi, Hamza
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Hybrid, composable approach to simulations in healthcare operations and management2017Ingår i: Proceedings of the 2017 Winter Simulation Conference / [ed] W. K. V. Chan, A. D'Ambrogio, G. Zacharewicz, N. Mustafee, G. Wainer, and E. Page, ACM Digital Library, 2017, Vol. F134102, s. 2857-2868Konferensbidrag (Refereegranskat)
    Abstract [en]

    Simulation has been used for modeling in healthcare for many decades. Ranging from the modeling of physiological processes to group dynamics to the modeling of strategic and system-wide models of healthcare provision, simulation promises to be an effective approach to analyze healthcare operations. Effective application of simulations in healthcare operations requires that simulation deal with wide variability and unpredictability in workflow processes, the complexity of healthcare organizations and enables the participation of human experts in the modeling and operations processes. In this paper, based on requirements drawn from a participatory simulation with healthcare practitioners, we define a hybrid, composable approach to healthcare simulations. Both the participatory simulation and the composable simulation are applied in the context of the New Karolinska Solna hospital in Sweden, a highly specialized new hospital. Results point to the need to accounting for variability in workflow processes and integration with existing IT infrastructure in hospitals. 

  • 21.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Complexity and Context: Meta-requirements for Simulation GamesIngår i: Simulation and Gaming, ISSN 10468781Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background. Simulations and models mediate between actors, and between actors and reality. Researching their context of use in policy making and their interpretation by policy makers is essential, since it might lead to different requirements and considerations for a modeler and the modeling process. 

     

    Aim. In this article, we investigate and attempt to define the demands and requirements policy makers might have from simulation models, especially in the context of decision making in complex systems. Another goal of this article is to contribute to the ongoing discussion on fidelity and validity, and their relationship with representation of systems in models.

     

    Method. Policy makers have expert knowledge of the systems they work with, as well as considerable experience in working with analytical tools such as simulations that provide them with evidence to support their policy processes. As potential clients and users of simulations, the reflections of 18 policy makers on the use of simulations are triggered through structured, play based exploration of a systems dynamics model. The system dynamics model simulates is specific to the local context and simulates the region they work in. It is implemented within Democracy 3, a commercially available game. This model is explored through game play in a workshop. Through forms and debriefing, insights were gathered from the players’ reflections on the use of models and simulations in policy practice.

     

    Results. Our results point to different requirements from policy makers on simulations and models. Policy makers prefer complete, open models which are flexible and facilitate exploration. Results also demonstrate the linked nature of fidelity and validity. 

  • 22.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH).
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH).
    Distributed, integrated and interactive traffic simulations2015Ingår i: Proceedings of the 2015 Winter Simulation Conference / [ed] L. Yilmaz, W. K. V. Chan, I. Moon, T. M. K. Roeder, C. Macal, and M. D. Rossetti, IEEE , 2015Konferensbidrag (Refereegranskat)
    Abstract [en]

    Mainstream discourse in urban planning is in transition, due to shifts from a technical to a communicativeperspective, and increased scrutiny and criticism of models and simulations. The cognizance of complexityin urban systems is imposing limitations on modeling. The added benefits of today’s data and compu-tational power make simulations harder to validate and understand. Reconciling the movements towardsa communicative and exploratory approach as compared to a technical and predictive approach requiresnew methods for planning process and posits new requirements and functions for simulations. Based ondistributed simulation and gaming simulation, the paper presents a framework to support the exploration ofsimulated and realistic virtual worlds in a participatory fashion, enabling new approaches to urban planning.The development and evaluation of the framework casts simulations in a new perspective and explores thecontext of use of simulations in planning and design.

  • 23.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Gaming, urban planning and transportation design process2015Ingår i: Lecture Notes in Geoinformation and Cartography, 2015, Vol. 213, s. 297-312Konferensbidrag (Refereegranskat)
    Abstract [en]

    In today’s urban planning, two perspectives dominate the discourse: a technical-rational perspective and a communicative rational perspective. Bridging the dichotomy between the two perspectives and situating new planning support methods within the context of complexity theories leads to new structures for planning support systems. The implications of the inherent complex nature of planning when bridging these perspectives should be taken into account for new planning processes and support systems. The development of such methods requires an iterative cycle between methodological and technological aspects of tool development. The chapter presents a technical framework that enables the development of methods integrating both perspectives. The framework derives its requirements from the integration of the two perspectives, and is evaluated in the context of two design case studies in the cities of Stockholm and Paris. The development of the framework and method has implications for the design of tools in urban planning. The tools need to reflect the open nature of the complex systems they represent and operate in. Such methods also expand the boundaries of the design space, allowing for previously unknown configurations.

  • 24.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Meijer, Sebastiaan
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Rigor in Gaming for Design: Conditions for Transfer Between Game and Reality2018Ingår i: Journal Simulation & Gaming, ISSN 1046-8781, E-ISSN 1552-826X, Vol. 49, nr 3, s. 246-262Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background. The increasing cognizance of complexity in systems has brought into focus important questions about the methods and tools we use to address them. Games for design, where games and computer simulations are used together to create concrete and tangible designs in a pluralistic way, with multiple stakeholders within the game is a new area for simulation gaming. Aim. In this article about gaming for design, embedded in the design science approach towards game science, we raise important philosophical questions about this new area, as well as attempt to address practical questions at the application level. We attempt to bridge the analytical science and design science approaches to games, and analyze them through meta-constructs of games such as fidelity, abstraction and resolution. Results. Results from two applications, through analysis of game play and debriefing of game sessions from two applications, COMPLEX and ProtoWorld are gathered and analyzed to understand the respresentational requirements for simulations and games. Conclusion. Results point to the need for rigor in gaming, particularly when modeling reference systems and rigor in assessing effects, both during game play and while debriefing. Results also point to expanded definitions of meta-constructs of games, as well as to their linked nature.

  • 25.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Trafik och logistik.
    Meijer, Sebastiaan A.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Trafik och logistik.
    A review of gaming simulation in transportation2014Ingår i: Frontiers in Gaming Simulation: 44th International Simulation and Gaming Association Conference, ISAGA 2013 and 17th IFIP WG 5.7 Workshop on Experimental Interactive Learning in Industrial Management, Stockholm, Sweden, June 24-28, 2013. Revised Selected Papers, Springer, 2014, s. 237-244Konferensbidrag (Refereegranskat)
    Abstract [en]

    Gaming simulation has proven to be an invaluable method for experimentation and learning and exploring scenarios in various fields of policy making. In this paper, we present a case for the use of gaming simulation in transportation analysis. We also present a review of games and gaming simulation in transportation analysis. We observe that gaming simulation is not widely used in transportation, despite its wide use in associated fields.

  • 26.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Moustaid, Elhabib
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Magal Shreenath, Vinutha
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap.
    Bridging borders: Integrating data analytics, modeling, simulation, and gaming for interdisciplinary assessment of health aspects in city networks2017Ingår i: City Networks: Collaboration and Planning for Health and Sustainability, Springer, 2017, s. 137-155Kapitel i bok, del av antologi (Refereegranskat)
    Abstract [en]

    The health perspective in urban science brings new methodological challenges to planning of city networks. Due to the system of systems nature of healthcare, new methods are needed to facilitate disciplinary integration and management of models and models-of-models. Participation of stakeholders and policy makers demands the uptake of new methods and a new perspective on the use of interfaces and boundary objects. In this chapter, the authors discuss evidence from five projects that use gaming, simulation, modeling, and data analytics in unconventional ways for design of large-scale urban systems to provide a methodological path forward for overcoming traditional engineering approach issues.

  • 27.
    Raghothama, Jayanth
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Shreenath, Vinutha Magal
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Analytics on public transport delays with spatial big data2016Ingår i: Proceedings of the 5th ACM SIGSPATIAL International Workshop on Analytics for Big Geospatial Data, BigSpatial 2016, ACM Digital Library, 2016, s. 28-33Konferensbidrag (Refereegranskat)
    Abstract [en]

    The increasing pervasiveness of location-aware technologies is leading to the rise of large, spatio-temporal datasets and to the opportunity of discovering usable knowledge about the behaviors of people and objects. Applied extensively in transportation, spatial big data and its analytics can deliver useful insights on a number of different issues such as congestion, delays, public transport reliability and so on. Predominantly studied for its use in operational management, spatial big data can be used to provide insight in strategic applications as well, from planning and design to evaluation and management. Such large scale, streaming spatial big data can be used in the improvement of public transport, for example the design of public transport networks and reliability. In this paper, we analyze GTFS data from the cities of Stockholm and Rome to gain insight on the sources and factors influencing public transport delays in the cities. The analysis is performed on a combination of GTFS data with data from other sources. The paper points to key issues in the analysis of real time data, driven by the contextual setting in the two cities.

  • 28.
    Roungas, Bill
    et al.
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Miguel, Baena
    Nommon Solutions and Technologies.
    Ros, Oliva García-Cantú
    Nommon Solutions and Technologies.
    Alcolea, Rubén
    Nommon Solutions and Technologies.
    Herranz, Ricardo
    Nommon Solutions and Technologies.
    Raghothama, Jayanth
    KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Medicinteknik och hälsosystem, Hälsoinformatik och logistik.
    Technology Adoption in Air Traffic Management: A Combination of Agent-Based Modeling with Behavioral Economics2021Ingår i: Proceedings of the 2021 Winter Simulation Conference, 2021Konferensbidrag (Refereegranskat)
    Abstract [en]

    The European Air Traffic Management (ATM) system is responsible for the safe and timely transportation of more than a billion passengers annually. It is a system that depends heavily on technology and is expected to stay on top of the technological advancements and be an early adopter of technologies. Nevertheless, technological change in ATM has historically developed at a slow pace. In this paper, an agent-based model (ABM) of the ATM technology deployment cycle is proposed. The proposed ABM is part of a larger project, which intends to recommend new policy measures for overcoming any barriers associated with technology adoption in ATM. It is a novel and one of the first approaches aiming at simulating the adoption of technology in ATM that combines the organizational point of view, i.e. stakeholders’ level, the focus on policy testing and the inclusion of behavioral economics aspects.

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  • 29.
    Shreenath, Vinutha Magal
    et al.
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Kornevs, Maksims
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    Raghothama, Jayanth
    Meijer, Sebastiaan
    KTH, Skolan för teknik och hälsa (STH), Hälso- och systemvetenskap, Vårdlogistik.
    A Feasibility Study for Gamification in Transport Maintenance: Requirements to implement gamification in heterogeneous organizations2015Ingår i: Games and Virtual Worlds for Serious Applications (VS-Games), 2015 7th International Conference on, IEEE conference proceedings, 2015, s. 1-7Konferensbidrag (Refereegranskat)
    Abstract [en]

    Gamification has been successfully applied in many domains, but mostly for simple, isolated and operational tasks. The hope for gamification as a method to radically change and improve behavior, to provide incentives for sustained engagement has proven to be more difficult to get right. Applying gamification in large networked organizations with heterogeneous tasks remains a challenge. Applying gamification in such enterprise environments posits different requirements, and a match between these requirements and the institution needs to be investigated before venturing into the design and implementation of gamification. The current paper contributes a study where the authors investigate the feasibility of implementing gamification in Trafikverket, the Swedish transport administration. Through an investigation of the institutional arrangements around data collection, procurement processes and links to institutional structures, the study finds areas within Trafikverket where gamification could be successfully applied, and suggests gaps and methods to apply gamification in other areas.

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