Endre søk
Begrens søket
1234 151 - 194 of 194
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Treff pr side
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sortering
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
Merk
Maxantalet träffar du kan exportera från sökgränssnittet är 250. Vid större uttag använd dig av utsökningar.
  • 151. Pieper, Rolf
    et al.
    Kager, L.
    Näsman, Per
    KTH, Tidigare Institutioner (före 2005), Infrastruktur.
    Clinical Significance of Mucosal Inflammation of the Vermiform Appendix1983Inngår i: Annals of Surgery, ISSN 0003-4932, E-ISSN 1528-1140, Vol. 197, nr 3, s. 368-374Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In 942 emergency appendectomies, the clinical data of 77 patients with inflammatory changes confined to the mucosa of the vermiform appendix were compared with data from 622 patients with diffuse acute appendicitis and 243 patients without evidence of inflammation in the appendix. In all cases, routine histologic sections of the specimens were reviewed. Of the 77 patients with mucosal appendiceal inflammation, 50 were female and 50% were under 17 years of age. In several clinical aspects, such as incidence of nausea, vomiting, migration of pain, and localized muscular rigidity, there existed significant differences between patients with mucosal inflammation and patients with diffuse appendicitis. Conversely, no statistically significant differences were found between patients with mucosal inflammation and patients without evident appendiceal inflammation. These results in addition to the frequent finding of histologically indistinguishable changes in appendices removed incidentally suggest that the condition is not responsible for the actual complaint.

  • 152. Quintana, M
    et al.
    Hjemdahl, P
    Sollevi, A
    Kahan, T
    Edner, M
    Rehnqvist, N
    Swahn, E
    Kjerr, A-C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Left ventricular function and cardiovascular events following adjuvant therapy with adenosine in acute myocardial infarction treated with thrombolysis.2003Inngår i: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041, nr 59, s. 1-9Artikkel i tidsskrift (Annet vitenskapelig)
  • 153. Quintana, M
    et al.
    Hjemdahl, P
    Sollevi, A
    Kahan, T
    Edner, M
    Rehnqvist, N
    Swahn, E
    Kjerr, A-C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Attacc Investigators, -
    Left ventricular function and cardiovascular events following adjuvant therapy with adenosine in acute myocardial infarction treated with thrombolysis - Results of the ATTenuation by Adenosine of Cardiac Complications (ATTACC) study2003Inngår i: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041, Vol. 59, nr 1, s. 1-9Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: Reperfusion therapy for acute myocardial infarction (AMI) reduces mortality but is also associated with reperfusion injury. The present study tested the hypothesis that adjuvant therapy with a low anti-inflammatory dose of adenosine might prevent reperfusion injury and preserve left ventricular function. Methods: Six hundred and eight patients with ST-elevation AMI were randomised to receive infusions of adenosine (10 mug.kg(-1)min(-1)) or placebo (saline) to be started with thrombolysis and maintained for 6 h. The primary endpoint was global and regional left ventricular systolic and diastolic function, as assessed by two-dimensional and Doppler echocardiography before hospital discharge. The secondary end-point was all cause and cardiovascular mortality, and non-fatal myocardial infarction during 12 months of follow-up. Results: No beneficial effect of adenosine was found regarding echocardiographic indices of left ventricular systolic or diastolic function. Recruitment was stopped due to this apparent lack of effect after an interim analysis. However, after 12 months of follow-up, cardiovascular mortality was 8.9% with adenosine and 12.1% with placebo treatment [odds ratio (OR) 0.71, 95% confidence interval (C.I.) 0.4-1.2, P=0.2] among all patients and 8.4% vs 14.6% (OR 0.53, 95% C.I. 0.23-1.24, P=0.09) among patients with anterior AMI. All cause mortality differed similarly. Non-fatal AMI was not reduced similarly by adenosine treatment. Survival curves indicate that possible survival benefits are maintained after the first year of follow-up. Conclusions: Adenosine, given as adjunctive treatment with thrombolysis, did not provide detectable improvement of echocardiographic indices of left ventricular function when assessed before hospital discharge. Cardiovascular and all cause mortality appear to have been reduced by low-dose adenosine treatment, and the size of the effect appears to be clinically relevant (absolute risk reductions of approximate to4%). The power of the study regarding morbidity and mortality was, however, limited. The results are compatible with a beneficial anti-inflammatory effect of adenosine treatment on reperfusion injury after thrombolysis, which may be mediated by inhibition of leukocytes in peripheral blood. A larger trial is warranted to possibly establish beneficial effects of low-dose adenosine on survival after thrombolysis.

  • 154. Quintana, M
    et al.
    Sollevi, A
    Rehnqvist, N
    Kahan, T
    Edner, M
    Swahn, E
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Kjerr, A-C
    Hjemdahl, P
    The effects of adenosine as adjuvant therapy in acute myocardial infarction on cardiovascular events: Results of the ATTenuation by Adenosine of Cardiac Complications (ATTAC) study2001Inngår i: European Heart Journal, ISSN 0195-668X, E-ISSN 1522-9645, Vol. 22, nr Supplement S, s. 287-287Artikkel i tidsskrift (Fagfellevurdert)
  • 155. Rathnayake, N
    et al.
    Buhlin, K
    Kjellström, B
    Klinge, B
    Löwbeer, C
    Norhammar, A
    Rydén, L
    Sorsa, T
    Tervahartiala, T
    Gustafsson, A
    PAROKRANK steering Committee; de Faire U.
    Lindahl, B
    Nygren, Å
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Svenungsson, E
    Saliva and plasma levels of cardiac-related biomarkers in post-myocardial infarction patients.2017Inngår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 44, nr 7, s. 692-699Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Aim: To relate cardiac biomarkers, such as cystatin C and growth differentiation factor-15 (GDF-15) in saliva to myocardial infarction (MI) and to periodontal status, and to investigate the relation between salivary and plasma cardiac biomarkers. Materials and Methods: Two hundred patients with MI admitted to coronary care units and 200 matched controls without MI were included. Dental examination and collection of blood and saliva samples was performed 6–10 weeks after the MI for patients and in close proximity thereafter for controls. Analysing methods: ARCHITECT i4000SR, Immulite 2000 XPi or ELISA. Results: The mean age was 62 ± 8 years and 84% were male. Total probing pocket depth, fibrinogen, white blood cell counts and HbA1c were higher in patients than controls. GDF-15 levels correlated with most of the included clinical variables in both study groups. No correlation was found between plasma and saliva levels of cystatin C or GDF-15. Conclusion: Salivary cystatin C and GDF-15 could not differentiate between MI patients and controls.

  • 156. Rathnayake, N
    et al.
    Gustafsson, A
    Norhammar, A
    Kjellström, B
    Klinge, B
    Rydén, L
    Tervahartiala, T
    Sorsa, T
    PAROKRANK Steering Group; de Faire U.
    Lindahl, B
    Nygren, Å
    Näsman, Per
    PAROKRANK Steering Group; de Faire U.
    Svenungsson, E
    Salivary Matrix Metalloproteinase-8 and -9 and Myeloperoxidase in Relation to Coronary Heart and Periodontal Diseases: A Subgroup Report from the PAROKRANK Study (Periodontitis and Its Relation to Coronary Artery Disease).2015Inngår i: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 10, nr 7, artikkel-id e0126370Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background and Objective: Matrix metalloproteinase (MMP) -8, -9 and myeloperoxidase (MPO) are inflammatory mediators. The potential associations between MMP-8, -9, MPO and their abilities to reflect cardiovascular risk remains to be evaluated in saliva. The objective of this study was to investigate the levels and associations of salivary MMP-8, -9, MPO and tissue inhibitors of metalloproteinase (TIMP)-1 in myocardial infarction (MI) patients and controls with or without periodontitis. Materials and Methods: 200 patients with a first MI admitted to coronary care units in Sweden from May 2010 to December 2011 and 200 controls matched for age, gender, residential area and without previous MI were included. Dental examination and saliva sample collection was performed 6-10 weeks after the MI in patients and at baseline in controls. The biomarkers MMP -8, -9, MPO and TIMP-1 were analyzed by time-resolved immunofluorescence assay (IFMA), Western blot and Enzyme-Linked ImmunoSorbent Assay (ELISA). Results: After compensation for gingivitis, gingival pockets and smoking, the mean salivary levels of MMP-8 (543 vs 440 ng/mL, p = 0.003) and MPO (1899 vs 1637 ng/mL, p = 0.02) were higher in non-MI subjects compared to MI patients. MMP-8, -9 and MPO correlated positively with clinical signs of gingival/periodontal inflammation while TIMP-1 correlated mainly negatively with these signs. The levels of latent and active forms of MMP-8 did not differ between the MI and non-MI groups. Additionally, MMP-8, MPO levels and MMP-8/TIMP-1 ratio were significantly higher in men compared to women with MI. Conclusions: This study shows that salivary levels of the analyzed biomarkers are associated with periodontal status. However, these biomarkers could not differentiate between patients with or without a MI. These findings illustrate the importance to consider the influence of oral conditions when analyzing levels of inflammatory salivary biomarkers.

  • 157. Rehnqvist, N
    et al.
    Hjemdahl, P
    Billing, E
    Björkander, I
    Eriksson, SV
    Forslund, L
    Held, C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Wallen, NH
    Effects of metoprolol vs verapamil in patients with stable angina pectoris: The Angina Prognosis Study in Stockholm (APSIS)1996Inngår i: European Heart Journal, ISSN 0195-668X, E-ISSN 1522-9645, Vol. 17, nr 1, s. 76-81Artikkel i tidsskrift (Fagfellevurdert)
  • 158. Rehnqvist, N
    et al.
    Hjemdahl, P
    Billing, E
    Björkander, I
    Eriksson, SV
    Forslund, L
    Held, C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Wallen, NH
    Effects on Cardiovascular End Points and Psychological Variables of Metoprolol and Verapamil in Patients with Stable Angina Pectoris: The Angina Prognosis Study in Stockholm (APSIS)1995Inngår i: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 25, nr 2 (Supplement 1), s. 313A-314AArtikkel i tidsskrift (Fagfellevurdert)
  • 159. Rehnqvist, N
    et al.
    Hjemdahl, P
    Billing, E
    Björkander, I
    Eriksson, SV
    Forslund, L
    Held, C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Wallen, NH
    Prevention of cardiac events in patients with angina pectoris: Results of the APSIS study1995Inngår i: European Heart Journal, Supplement, ISSN 1520-765X, E-ISSN 1554-2815, Vol. 16, nr Suppl. H, s. 18-18Artikkel i tidsskrift (Fagfellevurdert)
  • 160. Rehnqvist, N
    et al.
    Hjemdahl, P
    Billing, E
    Björkander, I
    Eriksson, SV
    Forslund, L
    Held, C
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Wallen, NH
    Treatment of stable angina pectoris with calcium antagonists and beta-blockers: The APSIS study1995Inngår i: Cardiologia, ISSN 0393-1978, Vol. 40, nr Suppl 1 al n 12, s. 301-301Artikkel i tidsskrift (Fagfellevurdert)
  • 161. Ritsinger, V.
    et al.
    Brismar, K.
    Malmberg, K.
    Mellbin, L.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Rydén, L.
    Söderberg, S.
    Tenerz, Å.
    Norhammar, A.
    Elevated levels of adipokines predict outcome after acute myocardial infarction: A long-term follow-up of the Glucose Tolerance in Patients with Acute Myocardial Infarction cohort2017Inngår i: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 14, nr 2, s. 77-87Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: Adiponectin and leptin are associated with insulin resistance and cardiovascular disease. Information on the prognostic value after an acute myocardial infarction is still conflicting. Methods: Patients (n = 180) without known diabetes and with admission glucose of <11 mmol/L admitted for an acute myocardial infarction in 1998-2000 were followed for mortality and cardiovascular events (first of cardiovascular mortality/acute myocardial infarction/stroke/heart failure) until the end of 2011 (median: 11.6 years). Plasma adiponectin and leptin were related to outcome in Cox proportional-hazard regression analyses. Results: Median age was 64 years and 69% were male. Total mortality was 34% (n = 61) and 44% (n = 80) experienced a cardiovascular event. Adiponectin at discharge predicted cardiovascular events (hazard ratio; 95% confidence interval; 1.45; 1.02-2.07, p = 0.038), total mortality (2.53; 1.64-3.91, p < 0.001) and cancer mortality (3.64; 1.51-8.74, p = 0.004). After adjustment for age, sex, body mass index, previous myocardial infarction and heart failure, adiponectin predicted total mortality (1.79; 1.07-3.00, p = 0.027) but not cardiovascular events. High levels of leptin were associated with cardiovascular events during the first 7 years, after which the association was attenuated. Leptin did not predict total mortality. Conclusion: In patients with acute myocardial infarction but without previously known diabetes, high levels of adiponectin at discharge predicted total mortality. The present results support the hypothesis that high rather than low levels of adiponectin predict mortality after acute myocardial infarction.

  • 162. Ritsinger, V.
    et al.
    Brismar, K.
    Mellbin, L.
    Näsman, P.
    KTH. 4Centre for Safety Research.
    Rydén, L.
    Söderberg, S.
    Norhammar, A.
    Elevated levels of insulin-like growth factor-binding protein 1 predict outcome after acute myocardial infarction: A long-term follow-up of the glucose tolerance in patients with acute myocardial infarction (GAMI) cohort2018Inngår i: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 15, nr 5, s. 387-395Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: To investigate the long-term prognostic value of insulin-like growth factor-binding protein 1 in patients with acute myocardial infarction. Methods: Patients (n = 180) with admission glucose < 11 mmol/L without previously known diabetes admitted for an acute myocardial infarction in 1998–2000 were followed for mortality and cardiovascular events (first of cardiovascular mortality/acute myocardial infarction/stroke/severe heart failure) until the end of 2011 (median 11.6 years). Fasting levels of insulin-like growth factor-binding protein 1 at day 2 were related to outcome in Cox proportional hazard regression analyses. Results: Median age was 64 years, 69% were male and median insulin-like growth factor-binding protein 1 was 20 µg/L. Total mortality was 34% (n = 61) and 44% (n = 80) experienced a cardiovascular event during a median follow-up time of 11.6 years. After age adjustment, insulin-like growth factor-binding protein 1 was associated with all-cause (1.40; 1.02–1.93, p = 0.039) and cancer mortality (2.09; 1.15–3.79, p = 0.015) but not with cardiovascular death (p = 0.29) or cardiovascular events (p = 0.57). After adjustments also for previous myocardial infarction, previous heart failure and body mass index, insulin-like growth factor-binding protein 1 was still associated with all-cause mortality (1.38; 1.01–1.89, p = 0.046). Conclusion: In patients with acute myocardial infarction without previously known diabetes, high insulin-like growth factor-binding protein 1 was associated with long-term all-cause and cancer mortality but not with cardiovascular events.

  • 163. Ritsinger, V
    et al.
    Brismar, K
    Mellbin, L
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS.
    Ryden, L
    Elevated levels of IGFBP-1 predict outcome after acute myocardial infarction. Long-term follow-up of the GAMI cohort.2017Inngår i: European Heart Journal, ISSN 0195-668X, E-ISSN 1522-9645, Vol. 38, artikkel-id P6470Artikkel i tidsskrift (Annet vitenskapelig)
  • 164. Ritsinger, V.
    et al.
    Brismar, Kerstin
    Malmberg, K.
    Mellbin, L.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Ryden, L.
    Soderberg, S.
    Tenerz, A.
    Norhammar, A.
    Elevated levels of adipokines predict outcome after acute myocardial infarction. Long-term follow-up of the GAMI cohort2016Inngår i: EUROPEAN HEART JOURNAL, ISSN 0195-668X, Vol. 37, s. 459-459Artikkel i tidsskrift (Fagfellevurdert)
  • 165. Ritsinger, V.
    et al.
    Tanoglidi, E.
    Malmberg, K.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande, Bygg- och fastighetsekonomi.
    Rydén, L.
    Tenerz, Å.
    Norhammar, A.
    Den prognostiska betydelsen av nyupptäckt glukosstörning hos patienter med akut hjärtinfarkt – en långtidsuppföljning av GAMI-studien.2015Inngår i: Best Practice, ISSN 1329-1874, nr 16, s. 18-21Artikkel i tidsskrift (Annet vitenskapelig)
  • 166. Ritsinger, Viveca
    et al.
    Tanoglidi, Eleni
    Malmberg, Klas
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Ryden, Lars
    Tenerz, Ake
    Norhammar, Anna
    Sustained prognostic implications of newly detected glucose abnormalities in patients with acute myocardial infarction: Longterm follow-up of the Glucose Tolerance in Patients with Acute Myocardial Infarction cohort2015Inngår i: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 12, nr 1, s. 23-32Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: To investigate long-term prognostic importance of newly discovered glucose disturbances in patients with acute myocardial infarction (AMI). Methods: During 1998-2001, consecutive patients with AMI (n=167) and healthy controls (n=184) with no previously known diabetes were investigated with an oral glucose tolerance test (OGTT). Patients and controls were separately followed up for cardiovascular events (first of cardiovascular mortality/AMI/stroke/heart failure) during a decade. Results: In all, 68% of the patients and 35% of the controls had newly detected abnormal glucose tolerance (AGT). Cardiovascular event (n=72, p=0.0019) and cardiovascular mortality (n=31, p=0.031) were more frequent in patients with newly detected AGT. Regarding patients, a Cox proportional-hazard regression analysis identified AGT (hazard ratio (HR): 2.30; 95% confidence interval (CI): 1.24-4.25; p=0.008) and previous AMI (HR: 2.39; CI: 1.31-4.35; p=0.004) as prognostically important. Conclusion: An OGTT at discharge after AMI disclosed a high proportion of patients with previously unknown AGT which had a significant and independent association with long-term prognosis.

  • 167. Ritsinger, Viveca
    et al.
    Tanoglidi, Eleni
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Malmberg, Klas
    Rydén, Lars
    Tenerz, Åke
    Norhammar, Anna
    The Long-term Impact of Newly Discovered Glucose Abnormalities in Patients With Acute Myocardial Infarction2013Inngår i: Circulation, ISSN 0009-7322, E-ISSN 1524-4539, Vol. 128, nr 22, s. 10261-Artikkel i tidsskrift (Annet vitenskapelig)
  • 168.
    Rudberg, Ann-Sofie
    et al.
    Karolinska Inst, Dept Clin Neurosci, Div Neurol, Tomtebodavagen 18A,Floor 5, S-17177 Stockholm, Sweden..
    Berge, Eivind
    Oslo Univ Hosp, Dept Internal Med & Cardiol, Oslo, Norway.;Univ Tromso, Inst Clin Med, Tromso, Norway..
    Gustavsson, Anders
    Quantify Res, Stockholm, Sweden.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden..
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för trafikforskning, CTR.
    Lundström, Erik
    Karolinska Inst, Dept Clin Neurosci, Div Neurol, Tomtebodavagen 18A,Floor 5, S-17177 Stockholm, Sweden..
    Long-term health-related quality of life, survival and costs by different levels of functional outcome six months after stroke2018Inngår i: European Stroke Journal, ISSN 2396-9873, E-ISSN 2396-9881, Vol. 3, nr 2, s. 157-164Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Introduction: Information about the impact of functional outcome after stroke is currently missing on health-related quality of life, survival and costs. This information would be valuable for health economic evaluations and for allocation of resources in stroke health care. Patients and methods: Data on 297 Swedish patients included in the Third International Stroke Trial were analysed including functional outcome at six months (measured by Oxford Handicap Scale), health-related quality of life up to 18 months (EQ-5D-3L) and survival up to 36 months. We used record linkage to collect data on costs up to 36 months, using national patient registers. Results: Patients with a better functional outcome level at six months had a significantly better health-related quality of life at 18 months (p<0.05), better long-term survival (p<0.05) and lower costs (p<0.001), for all time points up to 36 months. The difference in costs was mainly due to differences in days spent in hospital (p<0.005). Discussion: This study showed an association between functional outcome at six months and health-related quality of life up to 18 months, and costs up to 36 months. Conclusion: Functional outcome six months after stroke is an important determinant of health-related quality of life, survival and costs over 36 months. Effective interventions aimed at reducing short-term disability levels are therefore also expected to reduce the overall burden of stroke.

  • 169. Ryden, Lars
    et al.
    Buhlin, Kare
    Ekstrand, Eva
    de Faire, Ulf
    Gustafsson, Anders
    Holmer, Jacob
    Kjellstrom, Barbro
    Lindahl, Bertil
    Norhammar, Anna
    Nygren, Ake
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Rathnayake, Nilminie
    Svenungsson, Elisabet
    Klinge, Bjoern
    Periodontitis Increases the Risk of a First Myocardial Infarction A Report From the PAROKRANK Study2016Inngår i: Circulation, ISSN 0009-7322, E-ISSN 1524-4539, Vol. 133, nr 6, s. 576-583Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background The relationship between periodontitis (PD) and cardiovascular disease is debated. PD is common in patients with cardiovascular disease. It has been postulated that PD could be causally related to the risk for cardiovascular disease, a hypothesis tested in the Periodontitis and Its Relation to Coronary Artery Disease (PAROKRANK) study. Methods and Results Eight hundred five patients (<75 years of age) with a first myocardial infarction (MI) and 805 age- (mean 628), sex- (male 81%), and area-matched controls without MI underwent standardized dental examination including panoramic x-ray. The periodontal status was defined as healthy (80% remaining bone) or as mild-moderate (from 79% to 66%) or severe PD (<66%). Great efforts were made to collect information on possibly related confounders (approximate to 100 variables). Statistical comparisons included the Student pairwise t test and the McNemar test in 2x2 contingency tables. Contingency tables exceeding 2x2 with ranked alternatives were tested by Wilcoxon signed rank test. Odds ratios (95% confidence intervals) were calculated by conditional logistic regression. PD was more common (43%) in patients than in controls (33%; P<0.001). There was an increased risk for MI among those with PD (odds ratio, 1.49; 95% confidence interval, 1.21-1.83), which remained significant (odds ratio, 1.28; 95% confidence interval, 1.03-1.60) after adjusting for variables that differed between patients and controls (smoking habits, diabetes mellitus, years of education, and marital status). Conclusions In this large case-control study of PD, verified by radiographic bone loss and with a careful consideration of potential confounders, the risk of a first MI was significantly increased in patients with PD even after adjustment for confounding factors. These findings strengthen the possibility of an independent relationship between PD and MI.

  • 170.
    Sippl, Natalie
    et al.
    Karolinska Inst, Rheumatol Unit, Dept Med Solna, Karolinska Univ Hosp, Stockholm, Sweden..
    Grosso, Giorgia
    Karolinska Inst, Rheumatol Unit, Dept Med Solna, Karolinska Univ Hosp, Stockholm, Sweden..
    Ferrannini, Giulia
    Karolinska Inst, Dept Med Heart & Vasc Theme, Karolinska Univ Hosp, Stockholm, Sweden..
    de Faire, Ulf
    Karolinska Inst, Div Cardiovasc Epidemiol, IMM, Stockholm, Sweden..
    Lindahl, Bertil
    Karolinska Inst, Dept Clin Immunol & Transfus Med, Unit Clin Immunol, Karolinska Univ Hosp, Stockholm, Sweden..
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande, Bygg- och fastighetsekonomi.
    Norhammar, Anna
    Karolinska Inst, Dept Med Heart & Vasc Theme, Karolinska Univ Hosp, Stockholm, Sweden.;Capio St Gorans Hosp, Stockholm, Sweden..
    Ryden, Lars
    Karolinska Inst, Dept Med Heart & Vasc Theme, Karolinska Univ Hosp, Stockholm, Sweden..
    Svenungsson, Elisabet
    Karolinska Inst, Rheumatol Unit, Dept Med Solna, Karolinska Univ Hosp, Stockholm, Sweden..
    Amara, Khaled
    Karolinska Inst, Rheumatol Unit, Dept Med Solna, Karolinska Univ Hosp, Stockholm, Sweden..
    Domain specific anti-beta 2GPI antibodies in patients with First Myocardial Infarction2019Inngår i: Lupus, ISSN 0961-2033, E-ISSN 1477-0962, Vol. 28, s. 39-40Artikkel i tidsskrift (Annet vitenskapelig)
  • 171. Smaradottir, M I
    et al.
    Andersen, K
    Gudnason, V
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande, Bygg- och fastighetsekonomi. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS.
    Ryden, L
    Mellbin, L G
    Vasopressin, measured as copeptin, in elderly individuals with or without unrecognized myocardial infarction. A report from the ICELAND MI Cohort.2017Inngår i: European Heart Journal, ISSN 0195-668X, E-ISSN 1522-9645, Vol. 38, nr suppl_1, s. 863-864Artikkel i tidsskrift (Annet vitenskapelig)
    Abstract [en]

    Background: A subset of patients with myocardial infarction (MI) has minimal or no symptoms, i.e. clinically unrecognized MI (UMI). Copeptin, a marker of vasopressin, predicts cardiovascular events (CVE).

    Purpose: To investigate the prognostic implication of copeptin in people with or without MI and to study whether it differs between UMI and recognized MI (RMI).

    Methods: Copeptin was measured in 926 participants (age 76.0; male 48.5%) in the observational ICELAND MI study. At baseline 246 patients had hospital/surveillance records supporting a RMI (n=91) or myocardial scars detected by magnetic resonance imaging (UMI, n=155). Cox proportional hazard regression was used to assess the prognostic capability of (log) copeptin, in the multiple model adjusted for prior heart failure, fasting blood glucose, age groups and creatinine. The primary endpoint was CVE (cardiovascular death/MI/stroke/PCI/CABG) and the secondary endpoint was total mortality during 9.1 years of follow-up.

    Results: Copeptin levels were significantly higher in participants with compared to those without a MI (8.9 pmol/L vs. 6.4 pmol/L; p<0.01), but did not differ between the subsets with RMI vs. UMI.

    In the unadjusted analysis CVE:s were predicted by copeptin in the total cohort (HR 1.60; 95% CI 1.17–2.19; p<0.01) but not after adjustments (HR 1.18; 95% CI 0.84–1.65; p=0.33).

    Total mortality in the total cohort was predicted by copeptin in the unadjusted analysis. The same was found in patients with and without MI as well as in the subset with RMI, however, not in those with UMI. In the adjusted model copeptin remained as a predictor in the total cohort (HR 1.77; 95% CI 1.24–2.51; p<0.01), in all patients with MI (HR 2.20; 95% CI 1.25–3.87; p<0.01), and in those with RMI (HR 5.73; 95% CI 2.13–15.36; p<0.01).

    Conclusion: Copeptin levels were higher for participants with MI, however no difference was seen for those with RMI or UMI. Copeptin did not remain as a significant predictor for CVE after adjustments while it was an independent predictor for total mortality in patients with MI including the subset with RMI. This implies that copeptin is a general marker of disease rather than a specific marker for cardiovascular disease.

  • 172. Smaradottir, M. I.
    et al.
    Ritsinger, V.
    Gyberg, V.
    Norhammar, A.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för trafikforskning, CTR. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Mellbin, L. G.
    Copeptin in patients with acute myocardial infarction and newly detected glucose abnormalities - A marker of increased stress susceptibility?: A report from the Glucose in Acute Myocardial Infarction cohort2017Inngår i: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 14, nr 2, s. 69-76Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: To characterize copeptin levels and to explore its prognostic importance in patients with acute myocardial infarction with newly detected glucose abnormalities. Methods: Copeptin was measured in 166 patients with acute myocardial infarction without known diabetes and in 168 age- and gender-matched controls. Participants were classified as having normal glucose tolerance or abnormal glucose tolerance (impaired glucose tolerance + type 2 diabetes mellitus) by oral glucose tolerance test. Study participants were followed over a decade for major cardiovascular event (acute myocardial infarction/stroke/congestive heart failure/cardiovascular death), cardiovascular and total death. Results: Median copeptin level was higher in patients (10.5 pmol/L) than controls (5.9 pmol/L; p < 0.01). Patients with abnormal glucose tolerance had higher copeptin (12.2 pmol/L) than those with normal glucose tolerance (7.9 pmol/L; p < 0.01) but levels of copeptin did not differ in controls with abnormal glucose tolerance or normal glucose tolerance. Copeptin predicted major cardiovascular events [n = 64; hazard ratio = 1.15 (1.01-1.32; p = 0.04)], cardiovascular mortality [n = 29; hazard ratio = 1.24 (1.06-1.46; p = 0.01)] and total death [n = 51; hazard ratio = 1.21 (1.05-1.40; p = 0.01)] in unadjusted Cox regression analyses in the patient cohort. In controls, copeptin predicted major cardiovascular events [n = 26; hazard ratio = 1.17 (1.01-1.36; p = 0.03)]. Conclusion: Copeptin levels are highest among acute myocardial infarction patients with glucose disturbances and predict an adverse prognosis in unadjusted analyses. These findings imply that raised copeptin reflects stress rather than acting as a pathogenic factor for glucose abnormalities.

  • 173. Smardottir, MI
    et al.
    Mellbin, L
    Ritsinger, V
    Malmberg, K
    Norhammar, A
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Ryden, L
    Copeptin in patients with acute myocardial infarction and healthy controls with or without glucose abnormalities - a report from the GAMI trial.2014Inngår i: European Journal of Preventive Cardiology, ISSN 2047-4873, E-ISSN 2047-4881, Vol. 21, nr 1Artikkel i tidsskrift (Annet vitenskapelig)
  • 174. Stenquist, B
    et al.
    Rissler-Maier, K
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Local infiltration with ropivacaine 0.5% and mepivacaine 1.0% in patients operated upon for benign naevi: a double-blind comparison1994Rapport (Annet vitenskapelig)
  • 175. Svedberg, B
    et al.
    Holmkvist, K
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Kärrman, E
    Olika värdering av nyttan med återvinning2005Inngår i: RVF-nytt, ISSN 0284-1827, nr 2Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 176. Thedéen, T
    et al.
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Riskkontroll och riskanalys inom järnvägsområdet1992Annet (Annet vitenskapelig)
  • 177. Thedéen, T
    et al.
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Stokastiska modeller: ett verktyg för före-/efterstudier?1994Konferansepaper (Annet vitenskapelig)
  • 178. Ungerstedt, J. S.
    et al.
    Watz, E.
    Uttervall, K.
    Johansson, B. -M
    Wahlin, B. E.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS.
    Ljungman, P.
    Gruber, A.
    Axdorph Nygell, U.
    Nahi, H.
    Autologous hematopoietic stem cell transplantation in multiple myeloma and lymphoma: an analysis of factors influencing stem cell collection and hematological recovery2012Inngår i: Medical Oncology, ISSN 1357-0560, E-ISSN 1559-131X, Vol. 29, nr 3, s. 2191-2199Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Autologous stem cell transplantation is standard treatment for newly diagnosed younger patients with multiple myeloma and for relapsed or refractory Hodgkin or non-Hodgkin lymphoma. Patient characteristics influencing the yield from stem cell collection and time from transplant to platelet recovery were retrospectively analyzed in 630 consecutive patients, attempting to define adequate amounts of CD34+ cells to collect and reinfuse; 509/630 patients (81%) mobilized the requested CD34+ cell number. Factors influencing the harvest yield were age (P < 0.001) and gender, where 85% of men and 78% of women (P < 0.02) attained the requested stem cell amount. Time to platelet recovery was significantly faster for multiple myeloma patients compared to all other diagnoses (14.6 days compared to 19.8, P < 0.0001). Multiple myeloma patients were older than lymphoma patients but received stem cell transplant up-front as opposed to second line therapy for other patient groups. Multivariate analysis revealed that the most important factor influencing platelet recovery was diagnosis, followed by the amount of reinfused CD34+ cells (P < 0.001, P < 0.05). Blood group O+ had the fastest platelet recovery, whereas blood group A harvested the highest cell amounts. In conclusion, we demonstrate a significant importance of the number of reinfused CD34+ cells on the time to platelet recovery.

  • 179. Uttervall, Katarina
    et al.
    Andreasson, Johan
    Liwing, Johan
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Aschan, Johan
    Nahi, Hareth
    Follow up of multiple myeloma patients with renal impairment during a 10 year period2012Konferansepaper (Annet vitenskapelig)
    Abstract [en]

    Background. Renal impairment (RI) is a relatively common feature of multiplemyeloma (MM) and it has been shown in several studies that RI at diagnosiscorrelates to inferior survival, significant morbidity and increased early deathrate. Aims. To compare the efficacy of bortezomib-based treatment to otheranti-myeloma treatments during the course of the disease in patients presentingwith creatinine ≥130 μmol/L. The primary endpoint of the study was renalresponse (RR) in 1st, 2nd and 3rd line treatment. Time to progression (TTP), timeto next treatment (TTNT), overall survival (OS) and MM response were thesecondary endpoints.

  • 180. Uttervall, Katarina
    et al.
    Andreasson, Johan
    Liwing, Johan
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Aschan, Johan
    Nahi, Hareth
    Is Renal Impairment Still a Poor Prognostic Marker in Myeloma Care?: A Population Based Study Including 1542 Patients2012Inngår i: Blood, ISSN 0006-4971, E-ISSN 1528-0020, Vol. 120, nr 21Artikkel i tidsskrift (Annet vitenskapelig)
  • 181. von Arbin, M
    et al.
    Britton, M
    de Faire, U
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Factors of prognostic significance for the long-term outcome after stroke1989Inngår i: Atherosclerotic manifestations in stroke patients – Clinical and epidemiological studies.: Thesis, Magnus von Arbin, Department of medicine, Karolinska Instituet, Stockholm: Department of medicine, Karolinska Institutet , 1989Kapittel i bok, del av antologi (Fagfellevurdert)
  • 182. Wahlgren, N G
    et al.
    Sönderfaard, M
    Näsman, P
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Centra, Centrum för transportstudier, CTS. KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transport- och lokaliseringsanalys.
    Baseline adjustment did not increase the sensitivity of the Orogozo, Mathew and Barthel scales in the Intravenous Nimodipine West European Stroke Trial (INWEST).1996Inngår i: Cerebrovascular Diseases, ISSN 1015-9770, E-ISSN 1421-9786, Vol. 6, nr 2, artikkel-id P752Artikkel i tidsskrift (Annet vitenskapelig)
  • 183. Wang, A.
    et al.
    Arver, S.
    Flanagan, J.
    Mellbin, L. G.
    Gyberg, V.
    Malmberg, K.
    Norhammar, A.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transportvetenskap, Transportplanering, ekonomi och teknik.
    Ritsinger, V.
    Ryden, L.
    Testosterone in patients with acute myocardial infarction and glucose abnormalities and in matched controls: a report from the GAMI study2015Inngår i: Diabetologia, ISSN 0012-186X, E-ISSN 1432-0428, Vol. 58, s. S556-S557Artikkel i tidsskrift (Annet vitenskapelig)
  • 184. Wang, A
    et al.
    Arver, S
    Flanagan, J
    Mellbin, LG
    Gyberg, V
    Malmberg, K
    Norhammar, A
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande, Bygg- och fastighetsekonomi.
    Ritsinger, V
    Rydén, L
    Testosterone in patients with acute myocardial infarction and glucose abnormalities and in matched controls - a report from the GAMI study.2015Konferansepaper (Annet vitenskapelig)
  • 185.
    Wang, Anne
    et al.
    Karolinska Inst, Div Cardiol, Dept Med, S-17176 Stockholm, Sweden..
    Arver, Stefan
    Karolinska Inst, Dept Med, Ctr Androl & Sexual Med, Huddinge, Sweden..
    Flanagan, John
    Karolinska Inst, Dept Med, Ctr Androl & Sexual Med, Huddinge, Sweden..
    Gyberg, Viveca
    Karolinska Inst, Div Cardiol, Dept Med, S-17176 Stockholm, Sweden.;Karolinska Inst, Dept Neurobiol, Ctr Family Med Care Sci & Soc, Huddinge, Sweden..
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande, Bygg- och fastighetsekonomi.
    Ritsinger, Viveca
    Karolinska Inst, Div Cardiol, Dept Med, S-17176 Stockholm, Sweden.;Reg Kronoberg, Dept Res & Dev, Vaxjo, Sweden..
    Mellbin, Linda G.
    Karolinska Inst, Div Cardiol, Dept Med, S-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Heart & Vasc Theme, Stockholm, Sweden..
    Dynamics of testosterone levels in patients with newly detected glucose abnormalities and acute myocardial infarction2018Inngår i: Diabetes & Vascular Disease Research, ISSN 1479-1641, E-ISSN 1752-8984, Vol. 15, nr 6, s. 511-518Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: Low testosterone has been associated with increased cardiovascular risk and glucose abnormalities. This study explored the prevalence of low testosterone, dynamics over time and prognostic implications in acute myocardial infarction patients with or without glucose abnormalities. Methods: Male acute myocardial infarction patients (n = 123) and healthy controls (n = 124) were categorised as having normal or abnormal glucose tolerance (impaired glucose tolerance or diabetes) by oral glucose tolerance testing. Testosterone was measured at hospital admission, discharge, 3 and 12 months thereafter in patients. Patients and controls were followed for 11 years for major cardiovascular events (cardiovascular death/acute myocardial infarction/stroke/severe heart failure). Results: At hospital admission, more patients had low testosterone (<= 300 ng/dl) and lower median levels than controls (64 vs 28%; p < 0.001 and 243 vs 380 ng/dl; p < 0.01). At the subsequent time points, testosterone had increased to 311, 345 and 357 ng/dl. Patients with abnormal glucose tolerance had the highest prevalence (75%) of low levels. In adjusted Cox regression models, neither total nor free testosterone predicted major cardiovascular events. Conclusion: Low testosterone levels were common in male acute myocardial infarction patients in the acute phase, especially in the presence of abnormal glucose tolerance, but increased over time indicating that testosterone measured in close proximity to acute myocardial infarction should be interpreted with caution.

  • 186. Wilczek, M
    et al.
    Näsman, P
    Kälvesten, J
    Algulin, J
    Brismar, T
    Patients Who Will Suffer from a Hip Fracture Have Lower BMD when Analyzing Previously Obtained Standard Hand and Wrist Radiographs by Digital X-ray Radiogrammetry (DXR)2010Inngår i: Radiological Society of North America 2010 Scientific Assembly and Annual MeetingArtikkel i tidsskrift (Annet vitenskapelig)
  • 187.
    Ängskog, Per
    et al.
    KTH, Skolan för elektroteknik och datavetenskap (EECS), Elektroteknik, Elektroteknisk teori och konstruktion.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande. Center for Safety Research.
    Mattsson, Lars-Göran
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Fastigheter och byggande.
    Resilience to Intentional Electromagnetic Interference Is Required for Connected Autonomous Vehicles2019Inngår i: IEEE transactions on electromagnetic compatibility (Print), ISSN 0018-9375, E-ISSN 1558-187X, Vol. 61, nr 5, s. 1552-1559Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The connected autonomous vehicle (CAV) will never be completely autonomous; on the contrary, it will be heavily dependent on so-called vehicular ad hoc networks (VANETs) for its function. To deserve the trust of the general public, the vehicles as well as the intelligent transport system (ITS) infrastructure must be able to handle not only natural disturbances but also attacks of malicious nature. In this paper, we discuss the effects of antagonistic attacks using intentional electromagnetic interference (IEMI) and how the antagonistic nature of the threat renders probabilistic risk analysis inadequate for the defense of the vehicles and the infrastructure. Instead, we propose a shift toward resilience engineering and vulnerability analysis to manage antagonistic threats. Finally, we also give two examples of possible scenarios to illustrate the type of situations a CAV must be able to handle.

  • 188.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi (stängd 20110301), Säkerhetsforskning (stängd 20110301).
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi (stängd 20110301), Säkerhetsforskning (stängd 20110301).
    Factors Affecting Continuation of Smoking by Pregnant and Non-pregnant Women2009Inngår i: Substance Abuse, ISSN 0889-7077, E-ISSN 1573-6733, Vol. 30, nr 2, s. 150-157Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The objective of this study was to test a framework based upon the value and the probability of outcomes related to smoking. Over a 2-week period, 80 women were asked to perform judgments of value and probability of the outcome for smoking-related consequences. Subgroups were formed by the two variables of pregnancy and intent to quit smoking. Judgments were performed given the conditions of quitting and not quitting smoking. The intent to quit or not quit smoking had an impact on expected utility of smoking. Moreover, there was a difference between expected utility given the conditions of not quitting smoking and quitting smoking. A framework based upon values and beliefs appears to be useful in describing the addictive behavior of smoking and can be applied in developing smoking-cessation education.

  • 189.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Judgments of Risk for Consequences of Continuing or Quitting Smoking: A Study of Pregnant and Nonpregnant Women Intending and not Intending to Quit2008Inngår i: American journal of drug and alcohol abuse, ISSN 0095-2990, E-ISSN 1097-9891, Vol. 34, nr 2, s. 225-233Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

     Objectives: To study perceived smoking-related consequences of continuing and of quitting smoking. Methods: Eighty women, with subgroups formed by pregnant/nonpregnant women and trying/not trying to quit smoking, performed judgments of the probability for consequences to occur given the conditions of continuing or quitting smoking. Results: For both the pregnant and nonpregnant women, the probability that consequences will occur was rated as less likely given the condition of quitting smoking. The condition of quitting had its greatest effect on the probability that somatic consequences would occur. Conclusion: Consequences of smoking for somatic health should be stressed in health promotion, especially to pregnant women.

  • 190.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
     Perception of smoking-related health consequences among pregnant and non-pregnant women2007Inngår i: American Journal on Addictions, ISSN 1055-0496, E-ISSN 1521-0391, Vol. 16, nr 6, s. 521-527Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The objective was to examine the perception of smoking-related health consequences and its relationship to pregnancy and intent to quit. Over a two-week period, pregnant and non-pregnant women, intending and not intending to quit smoking, rated the probability for smoking-related health consequences to occur, given continuing to smoke and quitting smoking. Pregnant women who did not intend to quit smoking exhibited the lowest estimated probability for the smoking-related health consequences to occur if they continued smoking. For all women, there was a statistically significant estimated effect of quitting smoking. Renewed attention needs to be given to perceptions of health risks of smoking, especially among pregnant women.

  • 191.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Quitting smoking is perceived to have an effect on somatic health among pregnant and non-pregnant women2008Inngår i: The Journal of Maternal-Fetal & Neonatal Medicine, ISSN 1476-7058, E-ISSN 1476-4954, Vol. 21, nr 4, s. 239-246Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective. To examine the association of pregnancy and intent to quit smoking with perception of the somatic health risk of smoking and the effect on risk of quitting smoking. Methods. Pregnant and non-pregnant women, intending and not intending to quit smoking, (n = 80) over a two-week period rated the probability for smoking-related health consequences to occur, given both conditions of not quitting smoking and of quitting smoking. Results. Groups were the determining variable accounting for differences in risk perception. For pregnant women who did not intend to quit smoking, the estimated probability for the consequences to occur was generally low given the condition of continuing to smoke. There was no effect for time. The estimated effect of quitting smoking was statistically significant. Conclusions. Future campaigns need to integrate risk information so that it can be grounded cognitively in order to increase the personal responsibility that women take for their own health and the health of the fetus.

  • 192.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Somatic, psychological and social judgments related to smoking among pregnant and non-pregnant women2007Inngår i: Journal of Addictive Diseases, ISSN 1055-0887, E-ISSN 1545-0848, Vol. 26, nr 4, s. 69-77Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Purpose: To examine the association between pregnancy and judgments about a range of somatic, psychological and social events and conditions related to smoking. Basic Procedures: Pregnant and non-pregnant women smokers, intending and not intending to quit, were contacted in family practices in Bulgaria where they were under ordinary medical observation. All 80 women in the study were asked to rate consequences related to smoking in terms of how good or bad they were. Results: Being pregnant or not pregnant had the main effect on rated values of smoking-related consequences, with non-pregnant women giving the least positive ratings across the time-span of the study and whether or not they intended to quit. No statistically significant difference was obtained between the quitting and non-quitting women, and there was only one statistically significant difference for different days. Conclusions: The physical variable of pregnancy has a larger impact on judgments about smoking compared to the motivational aspect of intending to quit.

  • 193.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Use of coping techniques as a predictor of lapse when quitting smoking among pregnant and non-pregnant women2007Inngår i: American Journal on Addictions, ISSN 1055-0496, E-ISSN 1521-0391, Vol. 16, nr 3, s. 238-243Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    We examined the number of lapses among pregnant and non-pregnant women when trying to quit smoking, number of coping techniques used, and the relationship between any lapse and usage of coping techniques. Forty women were followed over a two-week period. On day 14, the women rated how often eleven different coping techniques were used. One-fourth of the women lapsed every day. If non-pregnant, the odds ratio was eight times higher compared to being pregnant for any lapse during the period. Being pregnant gives a higher success rate in attempts to quit smoking.

  • 194.
    Örtendahl, Monica
    et al.
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Uttermalm, Alf
    Simonsson, Bo
    Näsman, Per
    KTH, Skolan för arkitektur och samhällsbyggnad (ABE), Transporter och samhällsekonomi, Säkerhetsforskning.
    Wallsten, Tuula
    Estimated Time for Occurrence of Smoking-Related Consequences among Pregnant and Non-Pregnant Women2009Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objectives: To study time estimates by women smokers for when smokingrelated consequences will occur given continuing or quitting smoking. The relationship of these estimates to pregnancy and intent to quit smoking was also investigated. Methods: Over a two-week period, eighty women, selected to constitute four subgroups formed by pregnant vs. non-pregnant and trying vs. not trying to quit smoking, rated times at which they would expect smoking-related consequences to occur given continuing or quitting smoking. Results: Somatic health consequences were estimated to occur later than consequences related to mood and social relations. All consequences were estimated to occur later given quitting smoking. Pregnancy had an effect on the estimated time that consequences would occur, with pregnant women estimating earlier occurrence of consequences related to mood and social relations than non-pregnant women did. Conclusion: Health messages should stress consequences for somatic health in quitting smoking, since outcomes later in time might have too low a value to exert a positive effect on decisions to quit smoking.

1234 151 - 194 of 194
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf