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2026 (English) In: Advances in Building Energy Research, ISSN 1751-2549, E-ISSN 1756-2201Article in journal (Refereed) Epub ahead of print
Abstract [en] Indoor air quality (IAQ) plays a critical role in human health, yet indoor pollutants frequently accumulate despite improvements in ventilation and building design. Air cleaners are increasingly used as a complementary mitigation strategy, but their real-world effectiveness and clinical relevance remain heterogeneous. This review synthesizes evidence from 36 peer-reviewed studies to evaluate the pollutants targeted by air-cleaning technologies, their removal efficiency under realistic conditions, and their associations with respiratory, cardiovascular and other health outcomes. HEPA-based systems consistently reduce indoor particulate matter (PM), often by 20–80%, and show moderate evidence for short-term cardiopulmonary benefits, including reductions in blood pressure and inflammatory biomarkers. In contrast, evidence for gaseous pollutant removal, long-term health outcomes, cognitive effects and economic impacts remains limited, and some technologies may generate harmful byproducts such as ozone. The review also considers implications for vulnerable populations and energy-efficient buildings where ventilation may be constrained. By critically evaluating multidisciplinary evidence, this work bridges the gap between air-cleaning performance metrics and public-health relevance, supporting informed decision-making for practitioners, policymakers and building professionals.
Place, publisher, year, edition, pages
Informa UK Limited, 2026
Keywords HEPA filtration, Indoor air quality, air cleaners, energy-efficient buildings, human health outcomes, particulate matter
National Category
Occupational Health and Environmental Health Building Technologies
Identifiers urn:nbn:se:kth:diva-385557 (URN) 10.1080/17512549.2026.2692582 (DOI) 001809534000001 () 2-s2.0-105043761660 (Scopus ID)
Note QC 20260715
2026-07-152026-07-152026-07-15 Bibliographically approved