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Design of multivalent fluorescent dendritic probes for site-specific labeling of biomolecules
IBIMA Reg Univ Hosp Malaga UMA, Hosp Civil, Res Lab, Plaza Hosp Civil, Malaga 29009, Spain.;IBIMA Reg Univ Hosp Malaga UMA, Hosp Civil, Allergy Unit, Plaza Hosp Civil, Malaga 29009, Spain.;BIONAND Andalusian Ctr Nanomed & Biotechnol, Parque Tecnol Andalucia, Malaga 29590, Spain..
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Fibre- and Polymer Technology.
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Fibre- and Polymer Technology, Coating Technology.
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Fibre- and Polymer Technology, Coating Technology.ORCID iD: 0000-0002-8474-9478
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2018 (English)In: Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, E-ISSN 1099-0518, Vol. 56, no 15, p. 1609-1616Article in journal (Refereed) Published
Abstract [en]

Herein, the synthesis and characterization of orthogonal dendrons decorated with multiple units of fluorescent and a chemoselective group at a focal point, followed by specific antibody labeling, is presented. Fluorescence results confirm the applicability of the fluorescent probes for biomolecule labeling and fluorescent signal amplification.
Place, publisher, year, edition, pages
WILEY , 2018. Vol. 56, no 15, p. 1609-1616
Keywords [en]
antibodies, click chemistry, conjugation chemistry, dendrimers, dyes, fluorescence, imaging, multivalent labeling, polyester dendrons, selectivity
National Category
Polymer Chemistry
Identifiers
URN: urn:nbn:se:kth:diva-232228DOI: 10.1002/pola.29055ISI: 000436543800001Scopus ID: 2-s2.0-85049074485OAI: oai:DiVA.org:kth-232228DiVA, id: diva2:1233991
Funder
Knut and Alice Wallenberg Foundation, 2012-0196
Note

QC 20180720

Available from: 2018-07-20 Created: 2018-07-20 Last updated: 2024-03-15Bibliographically approved

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Stenström, PatrikAntunez, Pablo MesaAndrén, Oliver C. J.Malkoch, Michael

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Stenström, PatrikAntunez, Pablo MesaAndrén, Oliver C. J.Malkoch, Michael
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Fibre- and Polymer TechnologyCoating Technology
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Journal of Polymer Science Part A: Polymer Chemistry
Polymer Chemistry

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