This article introduces the special issue ?Brazilian Criminology in the 21st Century? that is composed of seven studies of contemporary security problems and related public security initiatives in Brazil. They are multidisciplinary contributions employing a large variety of methods, written by researchers based on Brazilian universities or research executed in cooperation with international colleagues. This is a unique and valuable reference source for researchers interested in Brazilian and Latin American security challenges as well as attempts to address them. By recognizing current barriers in knowledge production and sharing, the special issue calls for the creation of new opportunities for joint knowledge from the ?criminologies? of the Global South and those from the Global North, befitting an inclusive global criminology worthy of the 21st century.