The development of autonomous vehicle platoons will lead to new accident patterns. Insufficient research exists on occupant injury and protection associated with this new type of accident. To provide a reference for the research and technological development of occupant protection in autonomous vehicle platoon collisions, a continuous crash accident scenario involving a typical three-car autonomous vehicle platoon under high-speed conditions was utilized to determine boundary conditions such as impact time and speed. A full-scale finite element simulation was conducted to obtain the driver kinematics and injury response in each collision condition, and driver injury risk in the autonomous vehicle platoon collision scenarios was analyzed. The results show that although the risk of skull fracture is less than 1%, the risk of severe craniocerebral injury is significant, with the highest predicted risk of AIS 3+ using the BrIC criterion reaching 70.2%. Owing to excessive forward bending and backward extension of the cervical spine, three types of ligaments are at risk of serious injury. Furthermore, the risk of chest rib fracture is relatively low, whereas the risk of viscera damage is contingent on the collision sequence. When the middle car first experiences a frontal collision and is then rear-ended, the maximum principal strain on the driver's heart and liver far exceeds the damage threshold of 0.3, resulting in significant damage risk. Conversely, when the middle car is rear-ended and then collides with the front car, the maximum principal strain on the driver's internal organs is less than 0.3, resulting in a low overall damage risk.