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Algorithm for bone detection using low-count and low-resolution RF signals from a therapeutic sound wave probe
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Biomedical Engineering and Health Systems.
2025 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesisAlternative title
Algoritm för bendetektering med hjälp av RF-signaler med lågt antal och låg upplösning från en terapeutisk ljudvågssond (Swedish)
Abstract [en]

 Cardiac shockwave therapy (CSWT) is a promising non-invasive treatment for patients with refractory angina, aiming to stimulate myocardial regeneration by delivering acoustic energy to ischemic heart regions. However, the therapeutic CSWTprobeusedin this work has limited spatial resolution due to their low element count and large crystal sizes, making it difficult to detect and avoid bone structures such as ribs that can obstruct wave propagation towards the therapy target. This study presents a proof-of-concept algorithm designed to detect bone structures using low-resolution RF signals acquired with the therapeutic probe. The approach was implemented through ex-vivo phantom experiments using pork ribs, signal preprocessing, feature extraction, and machine learning algorithms. Multiple models were evaluated, achieving test accuracies above 82%, with Support Vector Machines and Ensemble Trees demonstrating strong performance. The standing-out models were able to reliably identify blocked elements in most probe positions, offering a potential method to guide probe orientation and optimize therapy.

Place, publisher, year, edition, pages
2025. , p. 39
Series
TRITA-CBH-GRU ; 2025:053
Keywords [en]
Cardiac Shockwave Therapy, Therapeutic Ultrasound, Bone Detection, Radiofrequency (RF) Signals, Machine Learning, Refractory Angina, Signal Processing
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-365572OAI: oai:DiVA.org:kth-365572DiVA, id: diva2:1976198
External cooperation
CSW Therapeutics
Subject / course
Medical Engineering
Educational program
Master of Science - Medical Engineering
Supervisors
Examiners
Available from: 2025-06-27 Created: 2025-06-24 Last updated: 2025-06-27Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
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Language
  • de-DE
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  • nn-NO
  • nn-NB
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  • Other locale
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Output format
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