An investigation of the response of sandwich structures subjected to impact velocities of virtually 0 m/s and approximately 1000 m/s is conducted. The higher velocity exceeds both the longitudinal and the transverse wave propagation velocities of the core material in the sandwich panels. The objective is to investigate the possibility to simulate the damage from ballistic impact of sandwich panels through quasi-static experiments. Panels are impacted using a 40 mm Bofors AA gun and, using a similar projectile, other panels are indented quasi-statically. Energy absorption is measured in both test series. After impact, the panels are tested in in-plane compression together with one undamaged panel for reference. Residual strength of impacted panels is analyzed by finite element analysis. It is shown that the damage from high-velocity impact is limited, and it is possible to regain most of the undamaged strength by repair.