This comprehensive Handbook presents thoughtful analysis on how regulations can impact innovation within a number of fields and markets, and provides a greater understanding of regulatory complexity and the challenging task it presents for future research. The Handbook of Innovation and Regulation embraces some of the key policy areas such as the regulation of markets, critical sectors, and global and regional aspects, focussing particularly on those regulations which target innovation. Reviewing these often interconnected policy areas in terms of both macroeconomic and microeconomic issues, this Handbook expertly studies how regulations in differing fields can affect innovative activities. By placing innovation centre stage, the contributors emphasise the direct and indirect effects of imposed regulations. Further, they illustrate the critically important overall impact of innovation to make firms competitive, promote economic growth and increase societal welfare. Addressing research and policy challenges, this Handbook would be an excellent resource for academics in regulatory economics, innovation and entrepreneurship, international trade, regional economics as well as environment and digitisation and policymakers in both national and international organisations.