Poly(vinyl acetate), PVAc, adhesives are commonly used for wood bonding; however, they are fossil-based and the final products usually do not have a sufficient water resistance for more durable applications. In this study we prepared an adhesive formulation by grafting VAc from chitosan using emulsion polymerization, chitosan-graft-PVAc. Thereby, we could decrease the fossil-based content of the adhesive and at the same time significantly improve the water resistance. Chitosan by itself has very good bonding properties as a wood adhesive, especially regarding water resistance; however, very low solid contents of the adhesive formulation can be achieved due to a very high viscosity of chitosan adhesives. In our chitosan-graft-PVAc adhesives, we explored two chitosan samples with different molecular weights, by using as-received chitosan and hydrolyzing it to a lower molecular weight. The chitosan fractions in the adhesives prepared with a higher molecular weight chitosan were 15, 20 and 25 wt%. However, due to the high viscosity, a solid content higher than 17 wt% could not be achieved for these adhesives. Sufficient bond strengths were achieved when the adhesive was applied in 122 g/m2 solid spread rate. In order to decrease the viscosity, we used hydrolyzed chitosan, with a lower molecular weight, to allow for a higher adhesive solid content, 34 wt%, and for a higher chitosan fraction, 40 wt%. In the adhesive with 40 wt% chitosan and 17 wt% solid content, all VAc was grafted from chitosan. This decreased the molecular mobility of the chains, leading to a lower susceptibility to plastic creep in the adhesive which contributes to the final bond strength. The dry and wet strengths of the specimens bonded with adhesives containing chitosan were higher than the strength of the specimens bonded with the reference PVAc adhesive.