The energy sector is one of the most sensitive base industries inThailandsince almost half of the total energy supply relies on imported sources. Of these, fossil fuels currently dominate electricity production. Exploring underutilized fuels like municipal solid waste (MSW) are vital towards securing a sustainable energy supply while minimizing greenhouse gas emissions. Moreover, a shift from MSW landfilling to incineration, if done with proper environmental controls, can also have positive benefits. This paper investigates the opportunities and potential for new MSW power plants with a focus on theBangkokregion, which produces up to 5 million tons of MSW per year. The energy recovery potential from MSW is analyzed by investigating various types of incineration technologies. In particular hybrid dual-fuel cycles, which integrate MSW and high-quality fuels like natural gas in an innovative fashion, are considered to be promising solutions. Study of plant performance in terms of efficiency and natural gas consumption from different power plant configurations are analyzed. An economic evaluation has been performed in this work to demonstrate the economic impact of the systems under consideration. Preliminary results show that MSW incineration has the potential to cover 8% ofThailand’s electricity; this amount is sufficient to meet the growth of national electrical consumption during a seven year span. InBangkokonly, power production via conventional incineration of MSW can achieve up to 2 TWh of electricity per year and this amount can be increased up to 3 TWh/yr if hybrid power plants employing integrated natural gas-fired topping cycles are employed. The maximum electrical efficiency increased by up to nearly 5% points for all hybrid cycles with natural gas to MSW fuel ratios of 0.3-0.4 NG. All proposed cycles (conventional and hybrid) are economically viable. The economic evaluation results also reveal that hybrid dual-fueled cycles are more economically acceptable compared to other alternatives.