Tunable Ampere phase plate for low dose imaging of biomolecular complexes Visa övriga samt affilieringar
2018 (Engelska) Ingår i: Scientific Reports, E-ISSN 2045-2322, Vol. 8, artikel-id 5592Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
A novel device that can be used as a tunable support-free phase plate for transmission electron microscopy of weakly scattering specimens is described. The device relies on the generation of a controlled phase shift by the magnetic field of a segment of current-carrying wire that is oriented parallel or antiparallel to the electron beam. The validity of the concept is established using both experimental electron holographic measurements and a theoretical model based on Ampere's law. Computer simulations are used to illustrate the resulting contrast enhancement for studies of biological cells and macromolecules.
Ort, förlag, år, upplaga, sidor NATURE PUBLISHING GROUP , 2018. Vol. 8, artikel-id 5592
Nationell ämneskategori
Den kondenserade materiens fysik
Identifikatorer URN: urn:nbn:se:kth:diva-228130 DOI: 10.1038/s41598-018-23100-3 ISI: 000429095600001 PubMedID: 29618785 Scopus ID: 2-s2.0-85044965282 OAI: oai:DiVA.org:kth-228130 DiVA, id: diva2:1207121
Anmärkning QC 20180518
2018-05-182018-05-182022-09-15 Bibliografiskt granskad