Digital accessibility has been the focus of initiatives, policies and standards at European and international level in the last decade. However, adoption of accessibility guidelines and the development of accessible resources and applications remain limited and education is a primary example of the multiple challenges that must be addressed. This research has highlighted the main barriers that should be overcome in order to make digital educational games accessible for learners with disabilities and it has brought forward the critical need of personalizing the game contexts and analytics to meet specific profiles of learners with disabilities. Building upon the outcomes of two case studies, the authors propose a game analytics framework for learners with disabilities, in an effort to streamline game design processes that target accessibility.