Thermal comfort has been the main target of the ventilation in subway systems. However, pollutant concen-tration and aerosol dispersion could be the leading health issues in underground metro stations. This study numerically simulated a train movement inside a subway system using the Dynamic Mesh Technique for a 3-D computational domain consisting of four stations and connecting tunnels. The effects of both the ventilation system and the train-induced fluid flow inside the subway system were investigated. Then, the particle gener-ation and dispersion due to train braking are considered, and the impact of the ventilation system on reducing the particle concentration inside the station was investigated. It is shown that the airflow inside the subway system is entirely affected by the piston effect. The airflow generated by the train movement is much higher than that generated by the operation of the ventilation system when only one train passes through the tunnel. The results show that the ventilation system, consisting of the supply and exhaust fans inside the tunnel and supply grilles inside the platform, can reduce the particle concentration by half, except for the platform beside the stopped train when the train enters the station and during half of the train stop time. The other design concept demonstrates that the under-platform exhaust system considerably reduces the concentration of the particles released by the train braking system on the trackside platform.