Very-high-energy neutrinos can be observed by detecting air shower signals. Detection of transient target of opportunity (ToO) neutrino sources is part of a broader multimessenger program. The Extreme Universe Space Observatory on a Super Pressure Balloon 2 (EUSO-SPB2) Mission, launched on May 12, 2023, was equipped with an optical Cherenkov Telescope (CT) designed to detect up-going air showers sourced by Earth-skimming neutrinos that interact near the Earth’s limb. Presented here is an overview of the sky coverage and ToO scheduler software for EUSOSPB2. By using the balloon trajectory coordinates and setting constraints on the positions of the Sun and Moon to ensure dark skies, we can determine if and when a source direction is slightly below the Earth’s limb. From a source catalog, CT scheduling and pointing is performed to optimize the search for high energy neutrinos coming from astrophysical sources. Some sample results for EUSO-SPB2 are shown.