This paper addresses the synchronization problemin open multi-agent systems containing both cooperative andantagonistic interactions. In these systems, new agents can join and new interactions can be formed over time. Moreover, the types of interactions, cooperative or antagonistic, may change. To model these structural changes, we represent the system as a switched system interconnected over a dynamic signed graph. Using the signed edge-based agreement protocol and constructing strict Lyapunov functions for signed edge-Laplacian matrices with multiple zero eigenvalues, we establish global asymptotic stability of the synchronization errors. Numerical simulations validate our theoretical results.