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Frequency dependent multiphase flows on centrifugal microfluidics
Iran Univ Sci & Technol, Sch Mech Engn, Tehran, Iran..
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Protein Science, Nano Biotechnology.ORCID iD: 0000-0002-2988-6445
Iran Univ Sci & Technol, Sch Mech Engn, Tehran, Iran..
Iran Univ Sci & Technol, Sch Mech Engn, Tehran, Iran..
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2020 (English)In: Lab on a Chip, ISSN 1473-0197, E-ISSN 1473-0189, Vol. 20, no 3, p. 514-524Article in journal (Refereed) Published
Abstract [en]

The simultaneous flow of gas and liquids in large scale conduits is an established approach to enhance the performance of different working systems under critical conditions. On the microscale, the use of gas-liquid flows is challenging due to the dominance of surface tension forces. Here, we present a technique to generate common gas-liquid flows on a centrifugal microfluidic platform. It consists of a spiral microchannel and specific micro features that allow for temporal and local control of stratified and slug flow regimes. We investigate several critical parameters that induce different gas-liquid flows and cause the transition between stratified and slug flows. We have analytically derived formulations that are compared with our experimental results to deliver a general guideline for designing specific gas-liquid flows. As an application of the gas-liquid flows in enhancing microfluidic systems' performance, we show the acceleration of the cell growth of E. coli bacteria in comparison to traditional culturing methods.

Place, publisher, year, edition, pages
ROYAL SOC CHEMISTRY , 2020. Vol. 20, no 3, p. 514-524
National Category
Mechanical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-276929DOI: 10.1039/c9lc00924hISI: 000536747300003PubMedID: 31898702Scopus ID: 2-s2.0-85079021527OAI: oai:DiVA.org:kth-276929DiVA, id: diva2:1444457
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QC 20200622

Available from: 2020-06-22 Created: 2020-06-22 Last updated: 2022-06-26Bibliographically approved

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Kazemzadeh, AminRussom, Aman

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CiteExportLink to record
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Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf