An Ultraminiaturized MEMS Microbiopsy Tool for Trans Blood Vessel Wall BiopsiesShow others and affiliations
2020 (English)In: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Institute of Electrical and Electronics Engineers (IEEE) , 2020, p. 10-12Conference paper, Published paper (Refereed)
Abstract [en]
We present a new type of microbiopsy tool (MBT) an order of magnitude smaller than commercially available biopsy catheters that, together with a trans-vessel wall catheter (Extroducer) successfully samples soft tissues with significantly less trauma to the tissue than commercial catheters. The MBT is mounted on a Nitinol wire. It features a gripping action that is actuated by the relative motion inside the Extroducer and has demonstrated repeated successful tissue sampling of approximately 500-1000 cells in ex-vivo tissue. This new catheter system can potentially allow super-selective, minimally invasive tissue sampling and transcriptomic analysis from hard to reach areas.
Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE) , 2020. p. 10-12
Keywords [en]
Biopsy, catheter, MEMS, minimally invasive, Blood vessels, Catheters, Mechanics, Tissue, Blood vessel walls, Microbiopsy tool, Nitinol wires, Relative motion, Soft tissue, Tissue sampling, Vessel walls
National Category
Medical Instrumentation
Identifiers
URN: urn:nbn:se:kth:diva-274234DOI: 10.1109/MEMS46641.2020.9056446ISI: 000569381600003Scopus ID: 2-s2.0-85083159075OAI: oai:DiVA.org:kth-274234DiVA, id: diva2:1452684
Conference
33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020, 18 January 2020 through 22 January 2020
Note
QC 20230328
2020-07-072020-07-072025-02-10Bibliographically approved