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Deep-learning-based motion artifact reduction for photon-counting spectral cardiac CT
KTH, School of Engineering Sciences (SCI), Physics. MedTechLabs, BioClinicum, Karolinska University Hospital, Solna, Sweden.
KTH, School of Engineering Sciences (SCI), Physics. MedTechLabs, BioClinicum, Karolinska University Hospital, Solna, Sweden.
KTH, School of Engineering Sciences (SCI), Physics. MedTechLabs, BioClinicum, Karolinska University Hospital, Solna, Sweden.ORCID iD: 0000-0002-5092-8822
2024 (English)In: Medical Imaging 2024: Physics of Medical Imaging, SPIE-Intl Soc Optical Eng , 2024, Vol. 12925, article id 1292507Conference paper, Published paper (Refereed)
Abstract [en]

Motion artifacts are among the most important factors degrading the diagnostic performance of x-ray CT images, in particular for photon-counting CT where these artifacts can degrade the higher spatial resolution and quantitative imaging capabilities. The purpose of this simulation study is to evaluate the capability of deep neural networks to correct for motion artifacts in spectral photon-counting cardiac CT, by generating motion-corrected virtual monoenergetic images at a range of different keVs. We used CatSim to generate synthetic training data by simulating motion-corrupted and motion-free CT imaging (100 kVp, 1 s rotation) of the dynamic XCAT phantom including heart and respiratory motion. In total 2160 image pairs were generated. We trained two different neural networks for the task of estimating motion-artifact-reduced images from motion-corrupted images: one based on UNet and one based on a Wasserstein generative adversarial network with a gradient penalty (WGAN-GP). To make these networks applicable to virtual monoenergetic images at different energies, we trained them with 40 keV and 70 keV monoenergetic images as inputs and used a loss function with two terms: 1) L1 -loss on soft tissue and bone basis images and 2) perceptual loss on 70 keV monoenergetic images. Our results show that the motion artifacts from 40 keV to 100 keV are reduced substantially. In conclusion, these results demonstrate the potential of image-domain deep neural networks to correct for motion artifacts in spectral cardiac CT images.

Place, publisher, year, edition, pages
SPIE-Intl Soc Optical Eng , 2024. Vol. 12925, article id 1292507
Series
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, ISSN 1605-7422 ; 12925
Keywords [en]
deep learning, Motion artifact, photon-counting CT
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-347138DOI: 10.1117/12.3006362ISI: 001223517100006Scopus ID: 2-s2.0-85193459965OAI: oai:DiVA.org:kth-347138DiVA, id: diva2:1864387
Conference
Medical Imaging 2024: Physics of Medical Imaging, San Diego, United States of America, Feb 19 2024 - Feb 22 2024
Note

QC 20240605

Part of ISBN 978-151067154-6

Available from: 2024-06-03 Created: 2024-06-03 Last updated: 2024-06-14Bibliographically approved

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Larsson, KarinPersson, Mats

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