As an alternative to rigid anodes, a novel concept of X-ray targets consisting of a stream or a multitude of streams of fast tungsten microparticles has recently been proposed. Low-density microparticle streams resemble thin targets with nearly constant intensity distribution over a wide range of photon energies, abruptly terminating at the Duane–Hunt limit of maximum photon energy instead of falling off smoothly. According to our simulations, fast microparticles outperform classical rigid targets and enable extremely high electronic input power density and X-ray output. This opens new possibilities for generating high-intensity, nearly monochromatic X-rays. Such keV-type X-ray sources could replace expensive electron synchrotrons in appropriate applications. Furthermore, for sufficiently thin microparticle streams, the output X-ray spectra are functions of particle size, allowing modulation of the mean photon energy. We simulated the spectral response of tungsten microparticles using Monte Carlo methods and confirmed the validity of our new concept to generate near-monochrome spectra and high intensity with microparticle-based X-ray sources, outperforming classical X-ray tubes. Furthermore, we confirm a weak size dependence of the mean energies of filtered X-rays. We complement previous results highlighting the advantages of microparticle-based X-ray targets and aim at the implementation of the new concept in the future.