This chapter describes a research thread at CITA which explores how computation and a challenging of traditional material practice can impact the use of timber in architectural design and fabrication. Several past research projects at CITA have demonstrated the potential for streamlining the design-to-production process using computational tools, and the value of working in concert with the inherent properties of wood. Current research continues this thread through a participation in the Innochain research network (http://innochain.net/) and collaboration with industrial partners White Arkitekter AB and Blumer-Lehmann AG. Through the embedding of digital tools within established timber design a fabrication processes, new workflows are proposed which could lead to more intelligent design decisions, optimized building components, and new timber morphologies.