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Comparative Analysis of Biological Networks by Control Theoretic Methods
KTH, School of Engineering Sciences (SCI), Mathematics (Dept.), Mathematics (Div.).
2022 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

This project deals with two Goodwin models of circadian rythms and three reduced models in understanding the Belousov-Zhabotinski models of chemical reaction. They are examined and compared by applying dynamical systems theory and control theoretical tools. More precisely, stability analysis of equilibria and the Hopf bifurcations. Moreover, we investigate the issues such as positivity and boundeness of the trajectories. Some are carried out by mathematical analysis and some are carried out by numerical simulations performed by Matlab. In particular, we provide a complete parameter description on stability of the Goodwin model in terms of the Hill number, which seems non-addressed in the literature.

Abstract [sv]

Detta projekt handlar om två Goodwin-modeller för cirkadiska rytmer och tre reducerade modeller för att förstå Belousov-Zhabotinski-modellerna för kemiska reaktioner. De undersöks och jämförs med hjälp av dynamiska systemteorier och kontrollteoretiska verktyg. Närmare besämt stabilitetsanalys av jämvikter och Hopf-bifurkationer. Dessutom undersöker vi frågor som positivitet och begränsning av banorna. En del av dessa undersökningar utförs genom matematisk analys och en del genom numeriska simuleringar som utförs med Matlan. I synnerhet ger vi en fullständig parameterbeskrivning av stabiliteten hos Goodwin-modellen i termer av Hilltal, som inte verkar ha behandlats i litteraturen.

Place, publisher, year, edition, pages
2022. , p. 64
Series
TRITA-SCI-GRU ; 2022:354
National Category
Other Mathematics
Identifiers
URN: urn:nbn:se:kth:diva-325870OAI: oai:DiVA.org:kth-325870DiVA, id: diva2:1751466
Subject / course
Optimization and Systems Theory
Educational program
Master of Science - Applied and Computational Mathematics
Supervisors
Examiners
Available from: 2023-04-20 Created: 2023-04-18 Last updated: 2023-04-20Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
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  • vancouver
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Language
  • de-DE
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More languages
Output format
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