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Electrical impedance myography combined with quantitative assessment techniques in paretic muscle of stroke survivors: Insights and challenges
Northwestern Polytech Univ Shenzhen, Res & Dev Inst, Shenzhen, Peoples R China.;Northwestern Polytech Univ, Inst Med Res, Xian, Peoples R China..
Sun Yat Sen Univ, Affiliated Hosp 1, Dept Rehabil Med, Guangzhou, Peoples R China..
KTH, School of Engineering Sciences (SCI), Engineering Mechanics. (KTH MoveAbil Lab)ORCID iD: 0000-0002-2232-5258
Northwestern Polytech Univ Shenzhen, Res & Dev Inst, Shenzhen, Peoples R China.;Northwestern Polytech Univ, Inst Med Res, Xian, Peoples R China..
2023 (English)In: Frontiers in Aging Neuroscience, E-ISSN 1663-4365, Vol. 15, article id 1130230Article in journal (Refereed) Published
Abstract [en]

Aging is a non-modifiable risk factor for stroke and the global burden of stroke is continuing to increase due to the aging society. Muscle dysfunction, common sequela of stroke, has long been of research interests. Therefore, how to accurately assess muscle function is particularly important. Electrical impedance myography (EIM) has proven to be feasible to assess muscle impairment in patients with stroke in terms of micro structures, such as muscle membrane integrity, extracellular and intracellular fluids. However, EIM alone is not sufficient to assess muscle function comprehensively given the complex contributors to paretic muscle after an insult. This article discusses the potential to combine EIM and other common quantitative methods as ways to improve the assessment of muscle function in stroke survivors. Clinically, these combined assessments provide not only a distinct advantage for greater accuracy of muscle assessment through cross-validation, but also the physiological explanation on muscle dysfunction at the micro level. Different combinations of assessments are discussed with insights for different purposes. The assessments of morphological, mechanical and contractile properties combined with EIM are focused since changes in muscle structures, tone and strength directly reflect the muscle function of stroke survivors. With advances in computational technology, finite element model and machine learning model that incorporate multi-modal evaluation parameters to enable the establishment of predictive or diagnostic model will be the next step forward to assess muscle function for individual with stroke.

Place, publisher, year, edition, pages
Frontiers Media SA , 2023. Vol. 15, article id 1130230
Keywords [en]
electrical impedance myography, stroke, skeletal muscle, spasticity, ultrasonography
National Category
Neurology
Identifiers
URN: urn:nbn:se:kth:diva-326483DOI: 10.3389/fnagi.2023.1130230ISI: 000961985300001PubMedID: 37020859Scopus ID: 2-s2.0-85153229832OAI: oai:DiVA.org:kth-326483DiVA, id: diva2:1754413
Note

QC 20230503

Available from: 2023-05-03 Created: 2023-05-03 Last updated: 2024-07-04Bibliographically approved

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Wang, Ruoli

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